⚠️56%—that the increased transmission of the B.1.1.7 🇬🇧 variant vs common strain from new study. Researchers warn that the #SARSCoV2 variant is so contagious that new control measures, including closing down schools and universities, may be necessary.🧵
nytimes.com/2020/12/23/hea…
2) authors warn variant must be taken very seriously. “I do feel that with the totality of the evidence, it’s a strong case”.

Dr. Davies et al projected what the new variant would do over the next six months and built models that factored in different levels of restrictions...
3) “Without a more substantial vaccine rollout, they warned, “cases, hospitalizations, I.C.U. admissions and deaths in 2021 may exceed those in 2020.”
4) “The study, released by Center for Mathematical Modeling of Infectious Diseases at the London School of Hygiene and Tropical Medicine, has not yet undergone peer review.

The study found no evidence that the variant was more deadly than others. (Corroborated by another study)
5) here is the other study that found no change in severity of the new B.1.1.7 variant. But due to exponential rise, that could be worse for total infectious and hospitalizations and deaths long term than a par-contagious & more severe strain.
6) Just now—Public Health England says "UNPRECEDENTED" LEVEL OF COVID INFECTION IS OF "EXTREME CONCERN" (pulled off the wires).
7) Back to the Davies study—they also found:

“Closing schools until February could buy Britain some time, the researchers found, but lifting those extra restrictions would then cause a major rebound of cases”
8) “Dr. Davies and his colleagues also took into account the protection that vaccines will provide. Vaccine experts are confident that coronavirus vaccines will be able to block the new variant, although that has to be confirmed by laboratory experiments that are now underway.”
9) “To look at the impact of the current rate of vaccinations, they modeled 200,000 people vaccinated/week. That pace was too slow to have much effect. “That kind of pace wouldn’t really be able to support much relaxation of any of the control measures,” Dr. Davies said.”
10) “But when they raised the vaccinations to **2 million a week**, they saw a reduction in the peak burden on I.C.U.s. Whether the U.K. can ramp up vaccinations by a **factor of 10** is unknown.”

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More from @DrEricDing

31 Dec
OMG. We epidemiologists just want to scream:

~20%-40% of Los Angeles County front-line workers declined #COVID19 vaccine.

So many in Riverside County refused that officials now strategizing how to distribute unused doses.

TAKE THE VACCINE FOLKS! Please.
latimes.com/california/sto… Image
2) Folks - both the Moderna and Pfizer vaccine are safe. Here is my summary of the Pfizer / BioNTech vaccine.
3) Here I walk folks thru the Moderna vaccine data. Also safe.
Read 5 tweets
31 Dec
⚠️NEXT LEVEL BAD—this radical change in ambulance 🚑 rules means if an EMT paramedic cannot resuscitate a heart beat, a patient will not be transported to any hospital in Los Angeles.

➡️This is worse than rationing 🏥 care. We have reached this. #COVID19
2) “These poor patients will be pronounced dead at the scene.”

Sobering. 😢
3) And even if you do get an ambulance 🚑, you may be turned away from the hospital in LA. Some hospitals now at 140% of capacity. It’s just that bad now. stay safe everyone. latimes.com/california/sto…
Read 5 tweets
31 Dec
Reinfection fears growing due to the other new South Africa 🇿🇦 discovered #SARSCoV2 variant (that shares the 501Y mutation w/ 🇬🇧 discovered B117). Not only faster spread, but SA experts noticing it coinciding with a lot of reinfections. Thread 🧵 #COVID19
wsj.com/articles/coron…
2) “Richard Lessells, an infectious-disease specialist—said its discovery has coincided with another worrying development: Doctors are reporting more patients, including health-care workers, who are testing positive for Covid-19 a 2nd time, after having had it in the first wave.”
3) “We are genuinely concerned, and that’s why we need to do research to understand this variant as quickly as we can,” Dr. Lessells and doctors treating Covid-19 patients in 🇿🇦 said they haven’t been able to prove whether these repeat positive tests are genuine reinfections—“
Read 5 tweets
30 Dec
BREAKING—the new more contagious U.K. 🇬🇧 #SARSCoV2 variant B.1.1.7 has been identified in California. More details to follow.

This confirms the previous California mutation identification chatter I mentioned the other day. #COVID19
2) More specifically, Gavin Newsom says the UK 🇬🇧 variant been found in SoCal.
3) Dr Fauci says, “I don't think Californians should feel this is something odd -- this is something expected."
Read 11 tweets
30 Dec
BREAKING—Oxford-AstraZeneca #COVID19 vaccine just approved for use in UK. Moreover, the vaccine campaign will now shift to giving as many people as possible their first dose—aim will be to give as many vulnerable people some protection. 🧵 bbc.com/news/health-55…
2) The decision is based on advice from the Joint Committee on Vaccination and Immunisation.

A spokesperson said: "The priority should be to give as many people in at-risk groups their first dose, rather than providing the required two doses in as short a time as possible.
3) “the Oxford-AstraZeneca vaccine will lead to a significant increase in vaccination as it is cheap and easy to mass produce.” — it is about 8-10x cheaper than the Pfizer / BioNTech or the Modern vaccines, and does not require freezing, just refrigeration.
Read 6 tweets
30 Dec
BREAKING—Sinopharm reports its inactivated virus #COVID19 vaccine had a 79% efficacy rate in interim late-stage trials. Last month, UAE 🇦🇪 reported Sinopharm’s vaccine had 86% efficacy (100% for moderate/severe COVID). 🧵
nytimes.com/2020/12/30/bus…
2) apparently UAE officials have already begun to use the Sinopharm vaccine as of last month based on its earlier 86% efficacy numbers.

Sinopharm vaccine does not require freezing.
3) Earlier— “The analysis shows no serious safety concerns,” the UAE Ministry of Health said, adding that the findings showed the vaccine was 100 percent effective in preventing moderate and severe cases of covid-19.

washingtonpost.com/world/asia_pac…
Read 4 tweets

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