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31 Dec 20, 10 tweets, 4 min read
I've been working with @13pt on a series of brief visual explainers for how different leading vaccines work. Here's a thread of links, starting with Novavax nytimes.com/interactive/20…
How the Pfizer-BioNTech vaccine works nytimes.com/interactive/20…
How the Moderna vaccine works nytimes.com/interactive/20…
How the Oxford-AstraZeneca vaccine works nytimes.com/interactive/20…
How the Johnson & Johnson vaccine works nytimes.com/interactive/20…
How the Sinovac vaccine works nytimes.com/interactive/20…
How the Sinopharm vaccine works nytimes.com/interactive/20…
That's all for now, but we'll roll out more as trials progress in 2021! /end
PS: Thanks to @mebottazzi @Virusnerdette @GuthmillerJenna & @florian_krammer for kindly providing their expertise
@mebottazzi @Virusnerdette @GuthmillerJenna @florian_krammer PPS And thanks also to @MattFrieman

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More from @carlzimmer

Carl Zimmer Profile picture
12 Oct 20
Vaccines are essential to fighting back the coronavirus. If one gets authorized in the next few months, what will that mean for 2021? One expert put it this way to me: get ready for “complexity and chaos and confusion.” Here’s my preview for @nytimes nytimes.com/2020/10/12/hea… 1/9
The first vaccine may be mediocre. A superior one may still be in development. But the first vaccine’s authorization could immediately affect all the other vaccines still in Phase 3 trials—and could seriously hamper vaccines in earlier stages of research. 2/9
To have enough doses for the whole country by the spring, the US government is counting on several vaccines getting emergency authorization. But guidelines for choosing between them could be very challenging, because their trials are all running separately. 3/9
Read 9 tweets
Carl Zimmer Profile picture
27 Aug 20
Thread: You may have heard of #COVID-19 vaccines in advanced clinical trials—Moderna, Pfizer, AstraZeneca and the like. But there’s a huge second wave of vaccines on their way. nytimes.com/2020/08/27/hea… [1/7]
I recently decided to take a look at this second wave. I reached out to all the companies and universities I could find that have announced preclinical studies since the beginning of the pandemic. [2/7]
I was able to confirm that 88 vaccines are still being actively investigated at the preclinical stage. Of these, 67 are on track to go into clinical trials in humans between now and the end of 2021. [3/7]
Read 7 tweets
Carl Zimmer Profile picture
20 Jul 20
Big morning for updates to the @nytimes coronavirus vaccine tracker. In fact, I need a thread! nytimes.com/interactive/20… 1/9 #covid19
First up: Oxford scientists publish their first clinical trial paper on their chimp adenovirus vaccine, to be made by Astra Zeneca. Phase I/II trial indicates it’s safe (lots of mild side effects), produces some antibodies, some interferon. 2/9
CanSinoBio has its own paper out in the Lancet, demonstrating an immune response to a vaccine based on another adenovirus, Ad5 3/9
Read 9 tweets
Carl Zimmer Profile picture
6 May 20
My Twitter ramblings yesterday have crystallized into a short piece on #covid19 mutations: nytimes.com/2020/05/06/hea…
Likewise, @edyong209 is on it theatlantic.com/health/archive…
@edyong209 A few key tips for reporting on mutation preprints...
Read 11 tweets
Carl Zimmer Profile picture
3 May 20
A lot of us science writers realized at some point a while back that we were going to be full-time #covid19 writers for a while. Maybe a very long while. Still, this past week felt especially bizarre, story-wise. An ICYMI thread 1/8
This week I helped put together this infographic: "How Coronavirus Mutates and Spreads" nytimes.com/interactive/20… (En espanol nytimes.com/es/interactive… ) 2/8
Working with @13pt on these visual explainers been a real privilege. Images can communicate some concepts so much better than words. Here’s a piece we did earlier on the SARS-CoV-2 genome: nytimes.com/interactive/20… and one on how the virus invades: nytimes.com/interactive/20… 3/8
Read 8 tweets
Carl Zimmer Profile picture
28 Apr 20
Trump cuts U.S. research on bat-human virus transmission over China ties politi.co/2KETSuN via @politico
@politico This type of research is literally how we know at all that this virus came from bats. And there are a lot more bat coronaviruses out there that have not been studied yet. They could become the Covid-20, Covid-21, Covid-22 and so on.
@politico Here is a tree showing the virus that causes #covid19 (red circle) and the virus that causes SARS (blue circle). Pangolin viruses in green. Bats in gray. LOTS OF BAT VIRUSES. And we have only found a tiny fraction of the bat viruses in this tree. biorxiv.org/content/10.110…
Read 5 tweets

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