Nearly 40 years after the first biotechnology companies began applying primitive genetic engineering techniques to bacteria and producing human proteins as therapeutics, the power of modern biotechnology is now on full display.
Once defined by endless experimentation and expensive and low probability-of-success drug development, biotech is at the leading edge, fusing rapidly advancing molecular science with a deterministic path to products and impact.
We've come a long way. We've learned about the human genome, its variations, and about bacterial species that occupy our gut affecting health & disease. We've learned to read, edit, write & regulate genomes--unimagined 5 yrs ago.
We are entering a new era of programmable medicines; they offer the possibility of fusing digital technologies with biotechnology to accelerate and increase the impact of new medicines, tackling everything from COVID to cancer.
These developments have given all of us in the field – permission to leap. Today, leaps to whole new fields and approaches are driven by the confidence borne of new knowledge, experience, capital, and capabilities.
Global need has also demanded we summon the courage to leap. Whether the COVID-19 pandemic, cancer, Alzheimer’s or other devastating diseases afflicting the planet, the urgent need to find cures or prevention requires big breakthroughs, like mRNA vaccines.
This is biotech’s moment to maximize its societal impact by continuing to make leap after leap: dramatically improving human health, global nutrition, and the sustainability of our planet demands that we do so.
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(1/7) Some experts are questioning whether vaccines will work to prevent #COVID19 - whether they should be tested in humans without more proof in animals first, whether they will increase viral activity rather than reducing it,..
.. (2/7) whether antibodies will be neutralizing, whether we need T Cell response instead, whether immune response will prevent the virus, whether the immunity will last, whether we can manufacture enough or distribute it appropriately, whether a vaccine can be ready in 12, ..
.. (3/7) 18, 24, 36, 60 months if ever? Other experts question whether anti-virals will work or whether monoclonal antibodies are enough to fight the virus, etc. Did I miss any expert concerns?....