After reading the post this afternoon, I read most of it out loud to my wife just now.

It was hard, because I was alternately laughing and crying.
Why does this move me so much? It's hard to explain.

As Scott says, it's just a blog, and at the same time, it's so, so much more.
Partly of course, I'm just happy he's back. I've positively missed his writing, which I've never felt about a blog. The insight, the humor, the incisive clarity, the relentless questioning, the exhaustive data analysis.
Scott asks big questions across a wide variety of domains and doesn't rest until he has clear answers. No, he doesn't rest until he can explain those answers to you lucidly. No, wait, he doesn't rest until he can do that and also make you laugh out loud.
At his best, he hits some strange triple point, previously undiscovered by bloggers, where data, theory, and emotion can coexist in equilibrium. And to me, at least, it's joy.
Most writing on topics as abstract and technical as SSC's struggles just not to be dry. I need a positive energy balance to read it; it takes effort to focus.

Scott's writing flows so well that it somehow generates its own energy, like some sort of perpetual motion machine.
I like to think that I'm pretty good at writing. I'm good enough that I convinced myself to quit my day job and to write instead of coding or managing, which I'm actually qualified for and which can definitely make you more money.

But I'm not nearly as good a writer as Scott.
Scott is so honest and fair that (to paraphrase @paulg) you can almost measure how depraved people are by how much they hate him.

I dislike bickering about politics on social media, but if anyone ever wants to take me down for praising SSC, I will fight them to the death.
But my emotional response to “Still Alive” wasn't primarily about being able to read a blog. Much as I love it, I doubt that alone could have moved me to tears.

Mostly, I was happy for Scott. Even though I barely know him, except through the blog.
Here's a guy just absolutely *loves* writing. It's so natural for him that he can't *not* write. More than a decade ago he had, what, a LiveJournal, and somehow he's now accumulated tens of thousands, maybe 100k fans.
And then a calamity strikes, and he decides that his only way out is to *take down the blog.* Like farmers torching their own fields as they retreat from an advancing army, destroying everything they built so as not to let it fall into enemy hands.
And for anyone else, that would have been the end of the story. But not for Scott, who decides to basically *rearrange his entire life*, including quitting his job and starting his own practice—in order to keep blogging.
(And, as a *side note* to this entire story, the new practice is incredibly interesting: “I'm going to try to start a medical practice that provides great health care to uninsured people for 4x less than what anyone else charges.” Godspeed.)
After the sudden and dramatic disappearance of the blog, after the outpouring of support from tens of thousands of fans, after six months of no SSC… he's back, and no one can ever threaten him in the same way again.

We were afraid this would kill him, but it made him stronger.
Someone once described public-key cryptography as the “fuck you” approach to key management. “Oh, you bastards want my encryption key? Well, fuck you, I'm just going to PUBLISH my key!”
I thought of that when I read the last line of Scott's post.

“Oh, you bastards want my real name? Well, fuck you, I'm just going to PUBLISH my real name!” Image
What a delightful up-yours to those who tried to expose Scott out of malice. (I don't mean the NYT; I agree with Scott's assessment that they didn't set out to harm him. I'm talking about others.)
Slate Star Codex is dead. Long live Astral Codex Ten!

And welcome back, Scott. We love you too.

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More from @jasoncrawford

28 Dec 20
Only three chapters into @CharlesCMann's *The Wizard and the Prophet* and why didn't anyone insist that I read this book before? Super-relevant to progress studies.

Just finished the Borlaug chapter, which is jaw-dropping, even though I already knew the Borlaug story in outline.
The sheer amount of hardship Borlaug endured, the setbacks, the lack of support from almost everyone around him, the tedium of crossing thousands of varieties and planting them by hand… all to save the world's hungry. Someone needs to make a movie out of this.
Seriously, there are so many great scenes. Usually science is hard to make dramatic on the big screen, but this would be fairly easy.

Like this scene where he has no equipment and no one will lend him any, so he literally pulls the plow through the field himself, like a mule:
Read 7 tweets
27 Dec 20
This image gets posted a lot lately, and not everyone knows what it means.

It's a reference to “survivor bias”: a statistical problem in which a sample is non-representative because some elements have been eliminated before the sample was taken. Here's a brief explainer.
The story: You're Britain. It's WW2. Your planes are getting shot down. You want to reinforce them with armor. But you can't armor the whole plane (for weight among other reasons).

What parts of the plane do you prioritize for armor?
Your researchers collect data on where your planes are getting shot. Whenever a plane returns from a mission, they note where they found bullet holes. This diagram shows all the holes that were found across many missions.

Given this data, where do you put the armor?
Read 14 tweets
17 Dec 20
If you want a single, vivid, and frankly disgusting example to hold in mind to remember how much our lives have improved over the last ~150 years…

Consider *shit*.

Literally, excrement. How much previous generations had to think about it, be around it, even handle it:
Before the automobile, horses flooded the streets, and cities were mired in their muck. According to Richard Rhodes, in NYC, horses dropped 4 million pounds of manure and 100 thousand gallons of urine on the streets every *day*. (!)
And Robert Gordon quotes this passage from *The Horse in the City*. “On New York’s Liberty Street there was a manure heap seven feet high.”

Shoveling shit was literally a full-time job. And one of the key uses of horses was to pull the wagons that carried away horse droppings.
Read 21 tweets
17 Dec 20
Good news.

A similar thing happened during the smallpox eradication program: a new applicator device, the “bifurcated needle”, used 1/4 the vaccine, and thus 4x'ed the supplies.
Close-up of a bifurcated needle, holding a drop of smallpox vaccine.

D. A. Henderson, who led the eradication program, made an award for his team called the “Order of the Bifurcated Needle.” His daughter made a patch showing the points of the needle bent into a zero.
Read 4 tweets
1 Dec 20
Today Google @DeepMind announced that their deep learning system AlphaFold has achieved unprecedented levels of accuracy on the “protein folding problem”, a grand challenge problem in computational biochemistry.

What is this problem, and why is it hard?

deepmind.com/blog/article/a…
I spent a couple years on this problem in a junior role in the early days of @DEShawResearch, so it's close to my heart. DESRES (as we called it internally) took an approach of building a specialized supercomputing architecture, called Anton: Image
Proteins are long chains of amino acids. Your DNA encodes these sequences, and RNA helps manufacture proteins according to this genetic blueprint.

Proteins are synthesized as linear chains, but they don't stay that way. They fold up in to complex, globular shapes. Image
Read 30 tweets
9 Nov 20
The 300-year history of vaccines as app updates:
~1720

v0.1 (beta): Inoculation

Features:
• Grants immunity
• Usually doesn't kill you

Known bugs:
• Mild disease symptoms
• You're still contagious and can start an outbreak

Supported platforms:
• Smallpox
1796

v1.0: Vaccination! Using new cowpox-based technology

Fixed:
• Doesn't kill you or start outbreaks
• Milder symptoms

Bugs:
• Immunity is temporary (booster shot upgrade packs required)

Supported:
• *Still* only smallpox
Read 8 tweets

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