Will it ever end? In November we were celebrating the announcements of several effective vaccines. Now hospitals are overwhelmed and the global death toll is climbing twice as fast as the worst days of the first wave.
At times like this, I reach for my calculator.
1/
There are two reasons why these vaccines, some highly effective, have not yet done anything obvious to save lives or protect hospitals.
The first is evident: not enough people have been vaccinated so far.
2/
The second reason is that the vaccine takes time to work. In the UK, Margaret Keenan received a first dose of vaccine bright and early on December 8, but it needs a couple of weeks to provide much protection. She and her fellow first-day vaccinees were safer by Christmas.
3/
But infections take time to develop into symptoms, symptoms take time to become serious enough to call for hospitalisation, and fatal cases take yet more time to develop. It takes weeks for vaccinations to make any impact on death statistics.
4/
Now for the good news. A small number of well-targeted vaccinations can have a huge effect.
The @COVID19actuary team reckon that 36% of all Covid-19 deaths in the UK's first wave (to late November) were among care home residents.
5/
Another 30% of deaths were among people aged 80 or more.
Collectively these groups are much less than 10% of the UK population. We have already delivered more than enough first doses to reach them all (although the exact targeting is unclear).
6/
It will take time for this to have an impact - but things may then start to move quite fast. The @COVID19actuary team project deaths reduced by two thirds by the end of February, relative to a no-vaccine scenario.
7/
For hospitalisations and ICU admission, it's a slower story because that is a younger population. But the same basic pattern applies: nothing seems to happen, then things happen quite quickly.
8/
So what could go wrong?
First, we might have missed large numbers of vulnerable people.
Second, the first dose might be much less effective than the provisional data suggest, at least among the elderly.
Third, the vaccination programme could stutter...
9/
...although even if it does, I think the UK, which is in an enviable position, has done a lot to protect large numbers of vulnerable people.
10/
What does this mean for 'lockdowns'?
I've always felt conflicted about them, but in the short term I think the case for voluntary and even compulsory distancing becomes a lot stronger. Instead of 'flattening the curve' you are permanently saving people from Covid-19.
11/
There is also the hope - as yet unproven - that vaccines might help prevent transmission. If so, the lockdowns will be more effective. 'Zero covid', something no major western country has managed to approach so far, starts to become feasible.
12/
It's like the vaccine and the lockdowns are both capable of fighting the virus - so why tag team? Why not send them both in at once to give it a really good kicking, fast?
(I realise this is a metaphor, not a data-driven epidemiological model. But still.)
13/
Anyway. I'm not an epidemiologist. Just a geek with a calculator and a newspaper column, very glad nobody has put me in charge of anything.
But at long last, I feel some hope.

14/
Oh - that column?
It's here: ft.com/content/42a98c…
15/
PS Not actually related, but if you have any friends in the US or Canada, do please tell them that my wonderful book is finally on sale over there...
timharford.com/books/datadete…

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More from @TimHarford

28 Jan
They called Abraham Bredius 'The Pope', a nickname that poked fun at his self-importance while acknowledging his authority. Bredius was the world's leading scholar of the mysterious Dutch master, Johannes Vermeer.
1/
When Bredius was younger, he’d made his name by spotting works wrongly attributed to Vermeer. Now, at the age of 82, he had just published a highly respected book and was enjoying a retirement swan song in Monaco.
2/
It was at this moment, in 1937, that Gerard Boon paid a visit to his villa. Boon, a former Dutch MP, came to Bredius on behalf of dissidents in Mussolini’s Italy. They needed to raise money to fund their escape to the US. Tthey had something which might be of value.
3/
Read 10 tweets
27 Jan
I’m delighted to be sharing a publication day, 2 February, with @AdamMGrant and his new book, Think Again. [UK: amzn.to/3oot17A] (US: amzn.to/3pp9PIb] Bookshop: uk.bookshop.org/lists/recent-r…
1/
Well, mostly delighted: that’s one fewer slot on the bestseller lists for me to aim for. Think Again is a stone cold classic and destined to do extremely well.
2/
The book explores three key areas: individual rethinking (the challenges and benefits of reconsidering your views); interpersonal rethinking (how do you get other people to think again?); and collective rethinking (can we shape a culture of respectful and engaged debate?).
3/
Read 19 tweets
22 Jan
Has there been a moment in modern history where so many people in free societies have believed such damaging lies?
ft.com/content/b25595…
1/
It’s easy to point to the US, where nearly 90 per cent of people who voted for Donald Trump believe Joe Biden’s election victory was not legitimate.
2/
But it’s not just the US. In France, a minority of adults are confident that vaccines are safe, which explains why only 40 per cent say they plan to get a Covid-19 shot.
3/
Read 17 tweets
21 Jan
1/ What a difference a few weeks makes. In mid-December, I asked a collection of wise guests on my BBC radio programme How to Vaccinate the World about the importance of second doses. bbc.co.uk/programmes/m00…
2/ At that stage, only economists - notably @Atabarrok – were suggesting giving people single doses of a vaccine instead of the recommended pair of doses. My panel roundly rejected this idea.
3/ But in the face of a shortage of doses and a rapidly spreading strain of “Super-Covid”, the scientific mainstream appears to have drifted. The UK’s policy is now to prioritise the first dose and to deliver the second one within three months rather than three weeks.
Read 14 tweets
13 Jan
1/ Things seem really bad at the moment. That's because things ARE really bad at the moment. But I wanted to share a perspective that might encourage you a little.
2/ Deaths have been so heavily concentrated among the elderly that even the current very limited vaccine rollout should have big benefits soon. Here's some back-of-the-envelope maths:
3/ As @ActuaryByDay told @BBCMoreOrLess a few weeks ago, more than a third of all Covid deaths in the first wave in the UK were among the few hundred thousand people who live in care homes residents. Another third were among people over the age of 80.
Read 8 tweets
20 Oct 20
HAPPY WORLD STATISTICS DAY EVERYONE!

World Statistics Day only comes every five years - like the Olympics - so it's time to express a little mindful gratitude for all the statisticians and other wonderful nerds out there helping us to understand the world.
Since I literally wrote the book on the topic, I’d like to mark the day by sharing my TEN RULES FOR THINKING DIFFERENTLY ABOUT NUMBERS. Each of us could be thinking more clearly about the world if we got ourselves right with the numbers. timharford.com/books/worldadd…
So, Rule One: SEARCH YOUR FEELINGS.
What we believe, or refuse to believe, is strongly influenced by our emotional reaction. A lot of the statistical claims we see aren’t just data: they are weapons in an argument. Social media thrives on emotion. So do media headlines.
Read 32 tweets

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