Fauci: “We have to be concerned about the mutants” 👀
He’s right on the concern for the #B117, #B1351, #P1. Plus the B117+E484K mutant combination is worrisome. #COVID19
2) Here are the mutations within each of the 3 standard variants. But the #B117 has also acquired the bad E484K mutation found in the SA and Brazil variants in a new B117 sublineage in Wales 🏴 and England. E484K is the bad one.
3) here is the detailed thread 🧵 of the new sublineage of B117 + E484K
5) 5) the E484K is the really bad mutation that gives the new variants that have it a degree of antibody immunity evasion. Not complete, but at least partial. This thread 🧵 gives you a rundown...
6) South Africa CDC found that of 44 people tested who had COVID last spring, when their blood (with antibodies) was tested against the new #B1351 variant pseudo virus, almost half had complete immune escape. 90% of them also had lower antibody binding.
7) moreover, the new E484K in B117 seems to have evolved separately in 2 different lineages of #B117 & somehow both **convergently evolved** to find E484K. here is the genome lineage @nextstrain map—one evolved in 🏴 and one separately in 🏴. Bad sign when you see convergence.
8) There is also a new preprint study that shows the Frankenstein #B117 + E484K has greater resistance to attempts at antibody neutralization (figures shows more antibodies needed to neutralize different types of the pseudovirus in lab experiment with the mutation).
9) Please take EXTRA precaution. Double mask with at least one being surgical or better grade, or switch to premium masks please ASAP.
10) Fauci was talking in the video above about this new stunning finding...
we are back to SQUARE ONE if we don’t stop these damn variants with tricky mutations that evade even our previous antibodies. look at what fresh hell we discovered this week...
🛑CANCELLED—“Research on Women’s Health” funding website of the NIH.
2) here is the page that is now deleted. Funding opportunities in women’s health research of ORWH site. Didn’t Trump say they at least recognize women as a gender? Weird.
🪓DELETION UPDATE—More than 1,000 pages are now deleted from websites of CDC, National Institutes of Health, and other sites of the Department of Health and Human Services, according to a new WSJ analysis—including many **vaccine recommendation** scientific pages!
2) CDC’s vaccine advisory committee webpage… now ❌ DELETED ❌
3) To be clear, while the main ACIP website is still up (generic committee info), the “VACCINE SPECIFIC RECOMMENDATIONS” website of ACIP has been **deleted**. That key page is the one with the actual public health info for vaccines. Feel free to verify:
⚠️CDC WEBSITES DELETED—Multiple CDC websites and datasets related to HIV, LGBTQ people, youth health behaviors and more have been removed after the agency was directed to comply with an executive order from President Trump by 5pm deadline. Wildest is taking down even HIV pages!
2) Like, why then hell did the “CAUSES” of HIV even get deleted??? Makes zero sense. Why is Trump WH wanting to block how to stop HIV??? cdc.gov/hiv/causes/ind…
3) also deleted: CDC’s Youth Risk Behavior Surveillance System, which includes data from a national survey, has disappeared. so have parts of the Agency for Toxic Substances and Disease Registry’s Social Vulnerability Index and the Environmental Justice Index.
⚠️Do you wonder why you haven’t heard much about this massive TB outbreak recently? Cuz the CDC can’t hold any press conferences or issue public statements of any kind.
➡️Most of the world 🌎 has been vaccinated against TB… but the US has not, which is now extra vulnerable.
2) For those asking, the majority of the world has used the BCG vaccine against TB… the BCG vaccine also protects against many other bacterial infections too. Up until now, CDC skipped it because US was low risk, and the BCG vaccine leaves a small scar & BCG messes up TB tests.
3) What about drugs for TB? Yes they exist but the problem is that TB often develops drug resistance (the bacteria evolves to evade neutralization). And thus, multi drug resistant TB has become a worldwide issue. That’s why childhood vaccination better. cdc.gov/tb/about/drug-…
⚠️PFAS IS BACK—recall the EPA plan to ban dangerous forever chemicals from drinking water ➡️Well, Trump WH just cancelled it… once again allowing big corporations to discharge PFAS into rivers. PFAS cause cancers & many diseases. Does this make American healthy again?
2) “There really isn’t a system within the human body that isn’t affected by PFAS. They are toxic in many ways, but they’re also very long-lived. They’re designed not to break down in the environment or not to break down to heat and chemical stress.” michiganpublic.org/politics-gover…
3) CDC also just got banned from seeking any advice or input from the WHO — CDC can’t communicate or even enter any WHO building anymore. Perfect way to politically isolate CDC from outside science.
NEW—CDC officially ordered by Trump WH to cease working with the @WHO, effective immediately. This is the first time in almost 77 years since WHO’s founding after World War 2. This is a dark day.
2) the memo said the stop-work policy applied to “all CDC staff engaging with WHO through technical working groups, coordinating centers, advisory boards, cooperative agreements or other means — in person or virtual.”
3) It also says @CDCgov staff are not allowed to visit @WHO offices.
CDC ordered to stop working with WHO immediately, upending expectations of an extended withdrawal