Eric Feigl-Ding Profile picture
Feb 4, 2021 10 tweets 6 min read Read on X
Fauci: “We have to be concerned about the mutants” 👀

He’s right on the concern for the #B117, #B1351, #P1. Plus the B117+E484K mutant combination is worrisome. #COVID19

2) Here are the mutations within each of the 3 standard variants. But the #B117 has also acquired the bad E484K mutation found in the SA and Brazil variants in a new B117 sublineage in Wales 🏴󠁧󠁢󠁷󠁬󠁳󠁿 and England. E484K is the bad one. Image
3) here is the detailed thread 🧵 of the new sublineage of B117 + E484K
4) and anyone with science degree or an X-men movie fan would know mutations are predictable when millions infected.
5) 5) the E484K is the really bad mutation that gives the new variants that have it a degree of antibody immunity evasion. Not complete, but at least partial. This thread 🧵 gives you a rundown... ?
6) South Africa CDC found that of 44 people tested who had COVID last spring, when their blood (with antibodies) was tested against the new #B1351 variant pseudo virus, almost half had complete immune escape. 90% of them also had lower antibody binding.
7) moreover, the new E484K in B117 seems to have evolved separately in 2 different lineages of #B117 & somehow both **convergently evolved** to find E484K. here is the genome lineage @nextstrain map—one evolved in 🏴󠁧󠁢󠁷󠁬󠁳󠁿 and one separately in 🏴󠁧󠁢󠁥󠁮󠁧󠁿. Bad sign when you see convergence. Image
8) There is also a new preprint study that shows the Frankenstein #B117 + E484K has greater resistance to attempts at antibody neutralization (figures shows more antibodies needed to neutralize different types of the pseudovirus in lab experiment with the mutation). Image
9) Please take EXTRA precaution. Double mask with at least one being surgical or better grade, or switch to premium masks please ASAP.
10) Fauci was talking in the video above about this new stunning finding...

we are back to SQUARE ONE if we don’t stop these damn variants with tricky mutations that evade even our previous antibodies. look at what fresh hell we discovered this week...

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More from @DrEricDing

Jun 23
📍 The New York Times Is Failing Its Readers Badly on Covid

📌“Example of ‘science opinion’ run amok in the [NY Times] is a piece… by Zeynep Tufekci, a commentator with no training in biological science or epidemiology… ➡️Tufekci plays into the hands of the anti-science politicians who now seek vengeance on the flimsiest of grounds.”

By GREGG GONSALVES and JOHN P. MOORE
thenation.com/article/societ…Image
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2) “Tufekci also adds to the ongoing pile-on about whether the directive to maintain a distance of six feet from others was needed. Although the precise distance was indeed somewhat arbitrary, there was no possibility of obtaining hard data in the relevant time frame. The six-foot distance was a reasonable assumption based on public health history, and the practice of social distancing for other respiratory pathogens, particularly those spread by droplets. It was also adopted in multiple other countries, for the same reasons.”
3) “The problem here isn’t that Tufekci is questioning the evidentiary basis of the six-foot rule—science and public health cannot progress if we don’t evaluate the results of our work. But that progress is more effective when grounded in good-faith inquiry, rather than the kinds of attacks Tufekci levels against government scientists for doing their best in desperate circumstances. This only serves to bolster the forces who seek to destroy the US public health infrastructure, not make it better.

Tufekci also leaves the impression that she alone realized SARS-CoV-2 was airborne early on. In fact, the debate about transmission was fast and furious within the scientific community at that time”
Read 9 tweets
Jun 17
⚠️Whooping cough has smashed all records in UK🇬🇧 with barely any serious govt actions. These are NEW CASES PER WEEK, not cumulative. Each week smashing previous. Other countries rising too amid anti-vax. Pertussis is also airborne!

Graph @1goodtern
gov.uk/government/pub…
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2) And yes it’s airborne damnit. CDC says so.

cdc.gov/pertussis/hcp/…
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3) Whooping cough is also extremely contagious. For up to 3 weeks. With UK govt advising staying home for 3 full weeks if no antibiotic treatment. How many people being told that and doing that?

nhs.uk/conditions/who…
Image
Read 8 tweets
Jun 12
⚠️SURGING COVID cases & hospitalizations in Madrid, Spain🇪🇸—hospitalizations for COVID has now exceeded also 2022-2023. This is the globally surging KP3 variant (US too)—it is highly evasive against past immunity—you’re not immune. Take preventive action.
comunidad.madrid/sites/default/…

Image
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2) New York City’s COVID cases are also increasing, as noted by @emmagf. June is not normal cold and flu season at all. This shows that this KP3 surging despite non-flu season means it’s a troublemaker. Image
@emmagf 3) Hawaii’s ERs also have gotten slammed hard by an off-season COVID surge. This isn’t normal at all for June. This is why we need to be on alert. Image
Read 8 tweets
Jun 11
📍Breaking—MASK BAN PASSED AGAIN—North Carolina Republicans have again voted to pass a new ban on mask wearing. Only a weak partial medical exemption added for PUBLIC areas—but, on private properties, like at grocery stores or at a workplace, the bill now says people can still be “REQUIRED TO REMOVE MASKS” if demanded by employer or owner (your health be damned). But, thank goodness Halloween masks will still be allowed.
motherjones.com/politics/2024/…Image
2) “Many healthcare professionals have expressed concerns that their patients would not be able to stay safe against the spread of Covid-19 and other infectious diseases.” Image
3) the scary thing is that “The bill, which was drafted in response to people wearing masks at Pro-Palestinian protests, can be passed by the General Assembly **even if Democratic Governor Roy Cooper vetoes** it through an override.”
Read 8 tweets
Jun 11
⚠️Our future cancer risks of #COVID are emerging and likely real. SarsCOV2 induces several of the same carcinogenic cellular changes as other viruses known to cause cancers. Most cancers take 10-20 years to fully emerge (eg 🚬 or HPV-cervical), but some cancers may emerge sooner.
2) “We are completely under-investigating this virus,” said Douglas C. Wallace, a University of Pennsylvania geneticist. “The effects of repeatedly getting this throughout our lives is going to be much more significant than people are thinking.”
wapo.st/3Rox991
3) We know from studies that Long COVID disease burden is already on par with the burden of heart disease and cancer. Now imagine if LC further stacks additional risks to these other major disease burdens in the decades to come.
Read 5 tweets
Jun 10
Cool time lapse of a dozen rapid Covid tests—by @jeremyfaust over 11 days. Staggeringly high viral load = rapid bright test line. CDC would have said it’s okay to go out on day 2. What a load of crap, and every epidemiologist I know agrees. #COVIDisnotover
2) this is why I’ve been adamant that @CDCDirector Cohen has morally abdicated CDC’s duty to disease “control and prevention” with her horrible leadership. And yes she was on board with this—she was at the press conference for relaxing Covid rules.
3) here is the full story about how @CDCDirector Cohen has just about done the worst thing to torpedo @CDCgov’s normally stellar reputation. More than Walensky and more than Trump CDC director Redfield.
Read 4 tweets

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