Thread by @profshanecrotty

Well, that's a nice surprise!
What happens if you have had COVID infection before and you get a COVID vaccine?

Some observations last week are summarized here:

https://twitter.com/profshanecrotty/status/1356623349862989827?s=20

In a new pre-print by the excellent @McGuire_Lab , they report a big jump in neutralizing antibodies after a single COVID RNA vaccine immunization (Pfizer or Moderna).

That is the same thing observed by @florian_krammer and the Sajadi labs.
medrxiv.org/content/10.110…

But, they also find that the immunized people now also make excellent neutralizing antibody responses to the South Africa variant! (B1351)

A massive jump in neutralizing antibodies.

First evidence that an immunization can elicit high neutralizing antibodies against the SA variant (B1351). I.e., the variant is not invisible to good human antibodies.