Nice to see this published
Working with @john_actuary from @COVID19actuary we’ve modelled impact of vaccination on
-deaths
-hospital admissions
-ICU admissions
Vaccinating just by age would have this impact on the three measures
The lag in the last two is because the groups differ.
Median ages
-deaths 83
-hospitalised 73
-ICU 61
So the cohort who might get to ICU have to wait for vaccination
If the graphs are adjusted to account for
-gp2 health/social care workers
-gp4 extremely clin vulnerable
-gp6 high risk
They look like this with lag slightly reduced (and the health service staff protected)
Vaccinating 15% of popln
-huge impact on deaths
-modest impact on ICU
Transforming into a timeline looks like this
A few implications
-steep slopes mean lots to gain in hospital & ICU admission by vaccinating beyond gps 1-4 (age >70)
-we need to vaccinate about 50% of adult population (gps 1-7) for significant impact on admissions
The curve arguably offers some support for the strategy of delaying 2nd vaccine dose as it enables penetration deep into the adult population within three months
After 50% of adult population vaccinated the curves flatten so there are questions/opportunities.
Should we vaccinate
-by age?
-key workers?
-the young (to stop spread)?
-another country (to help manage the global problem)?
The model is only that: ’a model’
With lots of assumptions
-100% take-up (in the over 60s)
-100% efficacy (at preventing severe disease)
-vaccine rate is maintained
We believe these are all reasonably justified
But we’ve modelled for lesser...
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Not sure altmetric is be-all & end-all but it looks like
the meta-analysis of ICU outcomes from COVID by @drrichstrong@adk300 has just become @Anaes_Journal no. 1 using that metric
Quite a feat during a pandemic while doing your day jobs
Well done🎩
Thanks @Anaes_Journal for publishing it and handling it so expertly and promptly, as usual
2/n
Unlike most papers this year it had a somewhat positive message showing how in-ICU mortality has fallen over the first months of the pandemic
- from around 60% in Jan-March
- to less than to 30% in May
An awful disease but one in which we have been making improvements