That’s not how this works.
That’s not how any of this works.
Viruses need one thing to mutate: a host. Protect the host, stop the mutations. We REALLY need to stop giving these people platforms when it’s blatantly obvious they have no idea what they’re freaking talking about.
For those asking what the issue is. This is a VERY misguiding message. Let me put it this way because no one is stating such even though they should be: it is FAR less likely for variants to occur in a vaccinated population than an unvaccinated population. Why? To put it simply:
This is basic virology. This virus isn’t exhibiting stress-induced mutagenesis. It is adapting solely to increase its fitness and that’s what it is selecting its mutations for- it isn’t adaptive immune pressure. This is happening only due to the fact it is infecting more people.
hence, more the more infections you have, the more mutations you have. Less infections through preventive vaccination, less mutations. This message by this individual gives those who disprove of vaccines all the ammunition they need- cause they’ll say what’s the point? Without
understanding how viruses really work because of tweets like this. If you have to follow up with: let me be clear, vaccination is the only way out of this pandemic and not remove your initial tweet because it got you attention in the first place, that’s a problem right there.
Oh! Also, we are talking about viruses NOT bacteria. The pressures that exist for bacteria concerning antibiotic resistance do not apply to viruses and vaccines. I don’t want to hear your theories; it’s not likely. If you don’t have data to back it up then don’t try to spin it.
Found the article I wanted to share in relevance to this. I highly recommend reading it! “Indeed, the evolution of vaccine resistance is so rare that vaccines are now considered a leading solution to the drug resistance problem.”
royalsocietypublishing.org/doi/10.1098/rs…

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More from @sailorrooscout

17 Feb
I want to bring this up. I’m sure by now you have seen those sensationalist headlines about variants merging and “heavily mutated hybrids” and what not. Guess what I want you to do right now? Ignore them. Yes, ignore them. Know why? Things like this are just mass hysteria. Image
The ones we need to be paying attention to are B.1.1.7, B.1.351 and P.1 because these are the only known SARS-CoV-2 variants that HAVE been shown to possess any evidence of functional significance or biological properties that make them a cause for concern to date. The rest?
Forget them. I read one article and I quote: “the recombination event may have occurred within the sample after it was taken from the infected person, not while it was inside their body. In which case it is an accidental laboratory artefact, not a wild virus.” Makes my head hurt.
Read 6 tweets
17 Feb
A new study out of Harvard offers evidence that SARS-CoV-2 variant B.1.1.7’s increased transmissibility isn’t due to its viral load but rather it’s delayed clearance, resulting in longer duration of infection. The implications are extremely positive. 🧵
dash.harvard.edu/bitstream/hand…
This could potentially mean a longer personal isolation period (longer than the currently recommended 10 days after symptom onset) may be all that is needed to control the spread of B.1.1.7! Image
For individuals infected with B.1.1.7, the mean duration of the proliferation phase was 5.3 days, the mean duration of the clearance phase was 8.0 days, and the mean overall duration of infection (proliferation plus clearance) was 13.3 days.
Read 5 tweets
17 Feb
Let’s discuss SARS-CoV-2 variants, selective pressure, and mutations. In the face of variants, our best protection is to get more people vaccinated. Vaccination will not automatically select for vaccine-resistant variants, especially if we can reduce transmission. Here’s why. 🧵
First, it is important to realize these vaccines will not drive the emergence of new variants and compel this virus to mutate in novel ways (OR create some scary super mutant so throw that idea out the window). I think this where a lot of the confusion lies- it’s not possible.
The specific mutations we are currently witnessing focus on altering the fitness of this virus by improving its rate of transmission with some signs of immune evasion. Mutation is a fairly constant process to begin with. It occurs randomly when a virus replicates and trust me,
Read 14 tweets
15 Feb
Certain “experts” should be quite ashamed for pushing fear mongering tweets and using misleading studies to fit their rhetoric concerning the efficacy of these vaccines. Since they rely on the fact most will not understand the studies since it’s not in layman’s terms allow me. 🧵
Firstly, the conclusions being drawn from this study and this “expert” is that the B.1.1.7 and B.1.351 variants would render these vaccines ineffective. This is highly unlikely. It will take a large amount of genetic diversity to completely render the current vaccines useless.
Not to mention Ding is using an older study to push this rhetoric when Pfizer and Moderna have recently established their vaccines will be effective against these variants. Perhaps someone should pass THOSE studies onto him. For the record, if you’re going to claim these vaccines
Read 14 tweets
15 Feb
More promising mRNA vaccine data!
This time from Moderna. A new Phase II study shows that half-doses (50 μg) of our vaccine appear to be as effective as full doses (100 ug) at eliciting robust immune responses in the form of neutralizing antibodies.🧵
sciencedirect.com/science/articl…
Participants were stratified into two age cohorts (≥18-<55 and ≥55) and were randomly assigned (1:1:1) to either 50 or 100 µg of mRNA-1273, or placebo administered as two intramuscular injections 28 days apart.
The primary outcomes were safety, reactogenicity, and immunogenicity assessed by anti-SARS-CoV-2-spike binding antibody level (bAb). Secondary outcome was immunogenicity assessed by SARS-CoV-2 neutralizing antibody (nAb) response. Participants had no history of infection.
Read 10 tweets
14 Feb
Good mRNA vaccine news this morning! Ben Osborn, the UK head of Pfizer, said they do not expect to have to change their vaccine to handle SARS-CoV-2 variants B.1.1.17 and B.1.351 due to no drop in efficacy! Let’s talk about variants, vaccines, and why you shouldn’t panic. 🧵
Firstly, we can agree media response to the variants has been overblown and become a huge source of misinformation unfortunately. For some context: you are going to read and hear about a TON of variant viruses, because viruses mutate by nature. Not every single one is a concern.
While I know it’s scary and a lot is “unknown,” a couple of amino acids is not the same a whole whole new virus strain in the way that we’ve been taught to think about influenza. RNA viruses by nature mutate more readily than DNA viruses. Not to mention, SARS-CoV-2 doesn’t
Read 14 tweets

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