I know you may have concerns about the new variants and whether our current vaccines will work against them. Some good news: a new lab study shows @pfizer 's vaccine offers solid protection against the variant first seen in South Africa aka B.1.351. (1/7)
Researchers tested an engineered version of the variant (B.1.351) against blood samples from people who had received two doses of the Pfizer-BioNTech vaccine (2/7)
There was a reduction in neutralizing antibody activity against the variant, but researchers said it was still enough to neutralize the virus. (3/7)
cnn.com/2021/02/17/hea…
Separately, another team of researchers said there were similar findings with the @moderna_tx vaccine. (4/7)
nejm.org/doi/full/10.10…
“Despite this reduction, neutralizing titer levels with (the variant discovered in South Africa) remain above levels that are expected to be protective,” Moderna said in a statement. (5/7)
Remember, though, these two studies were in a lab, so we still need to see how they would do in the real world. (6/7)
@JNJCares data does give us a better look at the efficacy of their vaccine in the real world -- since it was trialed when variants were circulating more widely. Importantly, J&J was still 85% effective in preventing hospitalizations and deaths. (7/7)

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More from @drsanjaygupta

18 Feb
It’s important to remember that coronaviruses mutate all the time. And, the more they spread, the more mutations can happen. That is why simply reducing transmission is the key to reducing new variants. (1/8)
So far we have identified variants by calling them things like B.1.1.7 or B.1.351, or associating them with where they were first identified. (2/8)
But, a group of researchers has found a better way - naming them after birds - or at least that’s what they did for a new crop of variants that they’ve found in the US. (I personally love the bird names -- naming variants like we name hurricanes) (⅜)
cnn.com/2021/02/14/hea…
Read 8 tweets
9 Feb
@CDCgov is expected to to release guidelines to reopen schools this week. So what do we know about keeping safe? One study found that over a 13 week period - schools in a Wisconsin district had a 37% lower incidence of infections relative to the surrounding community. 1/10
The report found that among the 191 cases detected in the schools - only 7 were from in-school spread. This is evidence that schools can be safe if (and this is an important if…) they have the resources to do it. 2/10
cdc.gov/mmwr/volumes/7…
Masks - More than 92% of students used masks. Students were provided with double or triple layer cloth masks. And both younger and older children used them. This is a great guide on the difference in masks. 3/10
Read 10 tweets
4 Feb
@JNJNews has officially submitted for emergency use authorization with the FDA. Last week we got the results for its Phase 3 Covid-19 vaccine trial. Here’s a thread on what we know about this vaccine. (1/13)
jnj.com/johnson-johnso…
Globally, here are the results for this single-shot vaccine.
This was from one month following the shot. (2/13)
That 85% figure is important because as Dr. Fauci of @NIAIDNews said, "If you can prevent severe disease in a high percentage of individuals, that will alleviate so much of the stress and human suffering and death." (3/13)
Read 14 tweets
4 Feb
We’ve been talking a lot about masks this past year. We know they protect us by reducing transmission of Covid-19, but when you buy a mask, do you know how much protection it offers? (1/6)
Here’s the @CDCgov guidance on masks. They still note that “Medical masks and N-95 respirators should not be used because they should be conserved for healthcare personnel.” (2/6) Source: CDC
The most important advice: wear a mask. But, as more high-quality masks become available and variants make the virus more transmissible, there is an important discussion happening about wider adoption of the highest-quality masks. (3/6)
cnn.com/2021/01/22/hea…
Read 6 tweets
15 Jan
President-elect @JoeBiden is about to present his $1.9 trillion #COVID19 relief plan. Let’s look at some of the key points: (1/12)
cnn.com/2021/01/14/pol…
1. Mount a national vaccination program - we all know it’s not going as quickly as planned. He wants to invest $20 billion in a national program that would include community vaccination centers and mobile vaccination units. (2/12)
He strongly believes that 100 million doses can be administered in 100 days -- even without additional vaccines. (3/12)
Read 12 tweets
18 Dec 20
My worlds collided today. While most of you know me as a reporter for CNN, my 'day job' is still: neurosurgeon. (1/11)
As a healthcare worker, it was my turn to get vaccinated today. And, I didn’t hesitate. (2/11)
As a journalist, I have covered the #COVID19 story for the last year — watching the entire process of the vaccine development, the regulatory process and reviewed the data myself. (3/11)
cnn.com/2020/12/11/hea…
Read 11 tweets

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