nature.com/articles/s4159…
Some thoughts on why these results don't mean much to me
1/ It was 2 weeks, which is short term and not enough time for adaptation (see point 8 and others on this)
2/ "Both diets were low in ultra-processed food" is a misrepresentation....
Some thoughts on why these results don't mean much to me
1/ It was 2 weeks, which is short term and not enough time for adaptation (see point 8 and others on this)
2/ "Both diets were low in ultra-processed food" is a misrepresentation....
...the low-carb diet was, IMO, unfairly weighted by processed foods and oils including mayo that I assume was made with soybean oil (correct me if I'm wrong), processed cheeses like "American cheese", and so on. It was also weighted towards meats and A1 dairy 
3/LC diet appears far more palatable, and both diets were designed by the investigators, not freely chosen by the participants. If my snack options were unlimited roasted salted nuts sitting in front of me or dry edamame, apricots, and raisins, I'd eat more kCal of nuts too.
4/ Tied to the prev comment, that's a complication of the metabolic ward. In free living population u seek food when u're hungry rather than having it presented. Plus, you have things to do and are less likely to eat out of habits that haven't been broken bc again it was 2 weeks
5/ there was no washout period, which is very odd for a crossover trial
6/ low-fat diet decreased energy burned at rest and while sleeping
7/ AND...
6/ low-fat diet decreased energy burned at rest and while sleeping
7/ AND...
7/ AND... the low-fat group did not lose more weight. they trended to lose less wight. if the investigators want to pin that on water loss the study should have been >2 weeks.
8/ back to 1, energy intake decreased in the low-carb group in week two. Do I smell adaptation?
8/ back to 1, energy intake decreased in the low-carb group in week two. Do I smell adaptation?
Concl. could go on but y? Any clinician who has tried low-fat vs low-carb for overweight patients in free living w real people over a reasonable period of time (wwell-formulated diet plans) that overall low-carb is more effective
-25:30
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.@garytaubes .@raphaels7 .@BrianLenzkes .@DoctorTro .@lowcarbGP .@DougieReynolds .@DrEades .@Ad_SotoMota ... your opinions?
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