The CDC says fully vaccinated people do not need masks or social distancing when meeting indoors with those at low risk for COVID-19. The rest of the guidelines are as follows. 🧵
The CDC defines people who are fully vaccinated as those who are two weeks past their second dose of the Moderna and Pfizer Covid-19 vaccine or two weeks past a single dose of the Johnson & Johnson vaccine.
The CDC says fully vaccinated people can:
-Visit other vaccinated people indoors without masks or physical distancing

-Visit indoors with unvaccinated people from a single family without masks or physical distancing, if the unvaccinated people are at low risk for severe disease.
-Skip quarantine and testing if exposed to someone who has Covid-19 but are asymptomatic, but should monitor for symptoms for 14 days

However, people who are fully vaccinated still need to take precautions in many scenarios. The guidelines say fully vaccinated people must:
-Wear a mask and keep good physical distance around the unvaccinated who are at increased risk for severe Covid-19, or if the unvaccinated person has a household member who is at higher risk

-Wear masks and physically distance when visiting unvaccinated people who are from
multiple households. In addition, fully vaccinated people should continue basic safety precautions, including: wearing a mask that fits well and keeping physical distance in public; avoiding medium- and large-sized crowds; avoiding poorly ventilated public spaces; washing hands
frequently; and getting tested for Covid-19 if they feel sick.
If fully vaccinated people live in a non-health care congregate setting, such as a group home detention facility, they should quarantine for 14 days and get tested if exposed to someone with a suspected or confirmed Covid-19 case.
The guidelines say that the risk of infection in social activities like going to the gym or restaurant is lower for the fully vaccinated, however, people should still take precautions as transmission risk in these settings is higher and increases the more unvaccinated are present
Lastly, the CDC travel recommendations have not changed for the unvaccinated. The guidelines still say that with high case numbers, the CDC recommends that you do not travel at this time. Remember that designated vaccination groups are expected to cease next month and with
increased vaccine supply and mass distribution efforts, all adults become eligible for vaccination so when you have the opportunity to get vaccinated please do.
Yes, I realize a lot of these guidelines are on the cautious side for acceptable reasons. The more we continue to prove these vaccines prevent transmission as more and more studies have shown the more lenient we can expect these guidelines to become.
Again, please don’t pounce on me. I didn’t make these guidelines I’m just a messenger and trying to get the information out there. Thanks guys. I humbly ask that everyone still remain vigilant and responsible. For more information please see: cdc.gov/coronavirus/20…

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More from @sailorrooscout

10 Mar
Let’s discuss SARS-CoV-2 variants, selective pressure, and mutations. In the face of variants, our best protection is to get more people vaccinated. Vaccination will not automatically select for vaccine-resistant variants, especially if we can reduce transmission. Here’s why. 🧵
First, it is important to realize these vaccines will not drive the emergence of new variants and compel this virus to mutate in novel ways (OR create some scary super mutant so throw that idea out the window). I think this where a lot of the confusion lies- it’s not possible.
The specific mutations we are currently witnessing focus on altering the fitness of this virus by improving its rate of transmission with some signs of immune evasion. Mutation is a fairly constant process to begin with. It occurs randomly when a virus replicates and trust me,
Read 14 tweets
10 Mar
Our immune systems are fascinating. This recent study on mRNA COVID-19 vaccines in naive and previously SARS-CoV-2 recovered individuals give us some much needed insight into antibodies and antigen-specific memory B-cells following 1st and 2nd doses. bit.ly/3rlfhwO 🧵 Image
There is limited data on vaccine-induced immune responses in individuals with a prior SARS-CoV-2 infection compared to those who have not had one as well as how mRNA vaccines impact the development of antibodies and memory B-cells in both of these groups.
To help study this, researchers evaluated antibody responses and antigen-specific memory B-cell responses over time in 33 SARS-CoV-2 naïve and 11 SARS-CoV-2 recovered subjects. Their findings are summarized below.
Read 14 tweets
8 Mar
Look at those antibodies!
The latest from the New England Journal of Medicine shows the effective neutralization assessed with serum from participants vaccinated with 2 doses of Pfizer’s BNT162b2 COVID-19 vaccine against VOCs B.1.1.7, B.1.351, and P.1.
nejm.org/doi/full/10.10…
To analyze effects on neutralization elicited by Pfizer’s vaccine, researchers engineered spike mutations from the from the current VOC lineages. They then performed 50% plaque reduction neutralization testing (PRNT50) using 20 serum samples that had been obtained from
15 participants in the pivotal trial 2 or 4 weeks after the administration of the second dose of 30 μg of Pfizer’s vaccine (which occurred 3 weeks after the first immunization). All the serum samples efficiently neutralized their isolate and all the viruses with variant spikes.
Read 6 tweets
8 Mar
Remember weeks ago when I spoke about variants, selective pressure, and convergent evolution? The emerging variants we see all seem to adapt the E484K escape mutation. What does this mean? It means SARS-CoV-2 might have just played its best card and its reaching its limit.
After mapping possible useful mutations of this virus, with E484K appearing to be of the most importance, we are possibly seeing the limits as to how far this virus can go. In the meantime, stay vigilant. Thank you @notdred for bringing this article up.
newyorker.com/science/medica…
So that no one is misinterpreting because I am seeing it already, this is meaning this might be the “worst” this virus can get. Also meaning, we are in a very good spot with more effective vaccine boosters on the way. We continue to stay on top of current VOCs with this mutation.
Read 5 tweets
7 Mar
I figured it was important to highlight this, especially when you might see fear-inducing headlines about this variant spreading quickly. B.1.1.7 now accounts for 20% of our cases in the U.S., HOWEVER we are seeing our lowest case counts now since October.
nytimes.com/interactive/20…
Even in states with low-restrictions we’re not seeing a resurgence in overall infections. While we are not fully in the clear yet, a combination of increased vaccinations, higher levels of natural immunity, and other mitigation efforts will help us avoid sharp spikes in cases.
Yesterday, the U.S. set a record of 2.9M vaccines administered, getting closer to the goal of 3M+ administered daily. This is the opportune time to gain an advantage with mass vaccination efforts as vaccine supply increases.
Read 5 tweets
7 Mar
Researchers in South Africa have found that antibodies of those previously infected with 501Y.V2 (B.1.351) are cross-reactive and thereby able to neutralize other variants of SARS-CoV-2 and prevent infection from other variants. Let’s discuss! 🧵
biorxiv.org/content/10.110…
Their research demonstrates immune response to B.1.351 is as potent as that seen in those infected with the original variant. Furthermore, antibodies from people infected with B.1.351 are not only able to neutralize B.1.351 but variant P.1 as well.
Blood samples from 89 patients in Cape Town, South Africa previously infected with SARS-CoV-2 were collected and sequenced. Their samples were all found to be that of B.1.351 by phylogenetic analysis. From previous accounts, we are aware that B.1.351 attributed to over 90% of
Read 15 tweets

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