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P. D. Mangan Health & Fitness Maximalist 🇺🇸

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11 Mar, 14 tweets, 5 min read

Industrial seed oils, aka vegetable oils, are still widely recommended as healthy.

But are they?

Thread 👇

Vegetable oils include a number of common cooking and dressing oils:

*canola
*soybean
*corn
*safflower
*sunflower
*and others

Note that they're not made from vegetables, but from seeds via an industrial process.

Olive and avocado oils are fruit, not seed, oils.

Until the late 19th century, these oils barely existed, and humans did not consume them.

But somebody got the bright idea of pressing the oil from cottonseeds, previously just a waste product.

Seed oils were born.

Seed oils are made by grinding large amounts of seeds and then subjecting them to chemical solvents, alkali, bleach, and deodorizers.

Not exactly normal human food.

Seed oils contain large amounts of linoleic acid, an omega-6 fatty acid.

Until ~1900, Americans ate ~1% of calories as linoleic acid.

They now consume about 9%.

Use of soybean oil exploded in the past few decades.

An unbalanced ratio of omega-6 to -3 fatty acids results in high amounts in tissues.

These in turn robustly associate with heart disease deaths.

Men who had had a recent heart attack and substituted saturated fats with safflower oil had a 62% increased all-cause death rate.
ncbi.nlm.nih.gov/pmc/articles/P…

Seed oils are a common ingredient in processed foods, since they're so cheap, and people think they're healthier than saturated fat.

Seed oils are a foundation of highly profitable ultra-processed foods.

Using seed oils to replace saturated fat lowers your cholesterol.

Unfortunately, every 30 point decrease in cholesterol leads to a 22% increased death rate.

HNE is an oxidized product of linoleic acid that's implicated in causing atherosclerosis and obesity.

ncbi.nlm.nih.gov/pmc/articles/P…

Potential harms of replacing saturated fats with seed oils include increased risk of cancer and heart disease.

In mice, soybean oil is more obesogenic and diabetogenic than sugar.

journals.plos.org/plosone/articl…

"soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer’s disease, anxiety, and depression. "

news.ucr.edu/articles/2020/…

In summary, seed (vegetable) oils are a recent introduction to the human diet, and we're not adapted to consuming them.

Abundant evidence points to their harmfulness.

Yet they're everywhere, and still touted for the alleged healthiness.

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More from @Mangan150

P. D. Mangan Health & Fitness Maximalist 🇺🇸

@Mangan150

13 Mar

Metabolic syndrome massively increases the risks for chronic disease.

What is it and why should you care?

Thread 👇

Someone has metabolic syndrome when they have at least 3 of the following 5 markers:

⬆️waist size
⬆️blood glucose
⬆️triglycerides
⬆️blood pressure
⬇️HDL cholesterol

Any 3 of those = metabolic syndrome

Any 1 = not 100% healthy

Metabolic syndrome is highly linked to obesity.

Metabolic syndrome is related to insulin resistance.

A classic study showed that people in the lowest third of insulin resistance had zero cases of heart disease, cancer, strokes etc.

Most were in the highest third.

Staying healthy means avoiding metabolic syndrome

Read 14 tweets

P. D. Mangan Health & Fitness Maximalist 🇺🇸

@Mangan150

9 Mar

Meat: does it harm your health

or is it in reality a superfood?

Let's take a look at the evidence.

Thread 👇

Everyone "knows" that meat is not healthy, but until a few decades ago, no one ever thought that.

Something changed.

What changed was the demonization of saturated fat as a cause of coronary heart disease by the (now notorious) Ancel Keys.

He used observational and cherry-picked data to "prove" his hypothesis.

Read 16 tweets

P. D. Mangan Health & Fitness Maximalist 🇺🇸

@Mangan150

7 Mar

Weird to realize that there are professional carbohydrate defenders, and that the health establishment confers advanced degrees in Carbohydrate Defense.

Why?

Leaving aside the merits or demerits of carbs, the answer IMO hinges on saturated fat, which the health establishment has told us to avoid for decades.

They told us to eat carbs instead.

Therefore, if carbs fall, the nutrition establishment falls.

It was all a pack of lies.

If you're lean and healthy and you exercise with intensity regularly, there's likely nothing wrong with some carbs.

Although you might be surprised when that bowl of "healthy" oatmeal spikes your blood sugar to 180.

Read 4 tweets

P. D. Mangan Health & Fitness Maximalist 🇺🇸

@Mangan150

7 Mar

Does insulin cause accelerated aging, and can you slow aging and live longer and in better health by keeping insulin levels low?

Let's look at the evidence.

Thread 👇

Insulin is a hormone secreted by the pancreas, which maintains normal blood glucose levels by promoting cellular glucose uptake, regulating carbohydrate, lipid and protein metabolism and promoting cell division and growth.

ncbi.nlm.nih.gov/pmc/articles/P…

Importantly, insulin resistance can occur, which is a lower response to insulin.

The result: insulin levels rise, leading to hyperinsulinemia.

Read 16 tweets

P. D. Mangan Health & Fitness Maximalist 🇺🇸

@Mangan150

5 Mar

You've probably heard about the importance of autophagy, but may have wondered what it is

By enhancing autophagy, we can live longer and in better health.

What is autophagy?

Thread 👇

Autophagy is the self-cleansing process that cells use to recycle junk molecules and organelles.

Cells constantly synthesize enzymes and structural molecules, which get damaged in the course of the life of the cell.

To function optimally, cells must break down and recycle these molecules that are past their expiration date and make new ones.

To do this, they use autophagy, a word derived from the Greek for "self-eating".

Read 14 tweets

P. D. Mangan Health & Fitness Maximalist 🇺🇸

@Mangan150

3 Mar

Hormesis is a fundamental concept in biology, and in health and disease.

Importantly, you can use hormesis deliberately to improve your own health and live longer.

What is hormesis?

Thread 👇

Hormesis is a process in which exposure to a low dose of a toxin or stressor that is damaging at higher doses induces an adaptive beneficial effect on the cell or organism.

Hormesis is ubiquitous in living things.

Hormesis is fundamental to living organisms' ability to survive and thrive against the assaults of the environment

Hugo Schulz discovered hormesis in 1884 when he noted that yeast cells grew better in the presence of low doses of chemical disinfectants.

Read 11 tweets

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