Meat: does it harm your health

or is it in reality a superfood?

Let's take a look at the evidence.

Thread ๐Ÿ‘‡
Everyone "knows" that meat is not healthy, but until a few decades ago, no one ever thought that.

Something changed.
What changed was the demonization of saturated fat as a cause of coronary heart disease by the (now notorious) Ancel Keys.

He used observational and cherry-picked data to "prove" his hypothesis.
In any case, numerous studies over the past decade have shown that saturated fat is not associated with coronary heart disease. academic.oup.com/ajcn/article/9โ€ฆ
The "evidence" that meat is harmful comes almost entirely from observational studies, which can show association, but not causation.

They are also fundamentally flawed by the use of food frequency questionnaires, which are "pseudoscientific" sciencedirect.com/science/articlโ€ฆ
Right away, we have national policy being set by pseudoscience, but even if questionnaires were valid, they can't show causation.

Furthermore, these studies are bedeviled by "healthy user bias". ncbi.nlm.nih.gov/pmc/articles/Pโ€ฆ
Healthy user bias is the propensity of someone who engages in one healthy behavior to do others, e.g. people who exercise are also likely not to smoke.

People have been told not to eat meat, and healthy users believed and obeyed. Others did not.
Furthermore, the evidence, such as it is, is exceedingly weak.

So weak, that a group of doctors and scientists, writing in the Annals of Internal Medicine in 2019, caused an uproar when they said there's no reason to curtail consumption of red and processed meat.
Many prominent members of the health establishment called for the censorship of this scientific article.

acpjournals.org/doi/10.7326/M1โ€ฆ
What about cancer?

Again, the evidence is extremely weak. Many studies have found no link with cancer, and others have found only weakly raised risks.

But weak relative risks are blown into major headlines by mainstream media.
"the currently available epidemiologic evidence is NOT SUFFICIENT to support an... association between red meat consumption and colorectal cancer." (my emphasis)

pubmed.ncbi.nlm.nih.gov/20663065/
What about vegetarians - aren't they healthier?

Healthy user bias again.

Recent studies show vegetarians do not live longer than meat eaters

academic.oup.com/ajcn/article/1โ€ฆ
Blue Zones are often cited, but

1. Blue Zones are not vegetarian, or even necessarily eat less meat.

2. Blue Zones may be fictitious entities.
Beef is a rich source of high-quality protein and vitamins and minerals, and is an excellent component of a healthy diet.

healthline.com/nutrition/foodโ€ฆ
If meat had not been demonized, we arguably might not have an obesity epidemic, as meat is the perfect weight loss food
In summary, the best evidence shows that meat is healthy.

The demonization of meat over the past few decades - and currently - is all a big mistake.

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More from @Mangan150

11 Mar
Industrial seed oils, aka vegetable oils, are still widely recommended as healthy.

But are they?

Thread ๐Ÿ‘‡ Image
Vegetable oils include a number of common cooking and dressing oils:

*canola
*soybean
*corn
*safflower
*sunflower
*and others

Note that they're not made from vegetables, but from seeds via an industrial process.

Olive and avocado oils are fruit, not seed, oils.
Until the late 19th century, these oils barely existed, and humans did not consume them.

But somebody got the bright idea of pressing the oil from cottonseeds, previously just a waste product.

Seed oils were born.
Read 14 tweets
7 Mar
Weird to realize that there are professional carbohydrate defenders, and that the health establishment confers advanced degrees in Carbohydrate Defense.

Why?
Leaving aside the merits or demerits of carbs, the answer IMO hinges on saturated fat, which the health establishment has told us to avoid for decades.

They told us to eat carbs instead.

Therefore, if carbs fall, the nutrition establishment falls.

It was all a pack of lies.
If you're lean and healthy and you exercise with intensity regularly, there's likely nothing wrong with some carbs.

Although you might be surprised when that bowl of "healthy" oatmeal spikes your blood sugar to 180.
Read 4 tweets
7 Mar
Does insulin cause accelerated aging, and can you slow aging and live longer and in better health by keeping insulin levels low?

Let's look at the evidence.

Thread ๐Ÿ‘‡
Insulin is a hormone secreted by the pancreas, which maintains normal blood glucose levels by promoting cellular glucose uptake, regulating carbohydrate, lipid and protein metabolism and promoting cell division and growth.

ncbi.nlm.nih.gov/pmc/articles/Pโ€ฆ
Importantly, insulin resistance can occur, which is a lower response to insulin.

The result: insulin levels rise, leading to hyperinsulinemia.
Read 16 tweets
5 Mar
You've probably heard about the importance of autophagy, but may have wondered what it is

By enhancing autophagy, we can live longer and in better health.

What is autophagy?

Thread ๐Ÿ‘‡
Autophagy is the self-cleansing process that cells use to recycle junk molecules and organelles.

Cells constantly synthesize enzymes and structural molecules, which get damaged in the course of the life of the cell.
To function optimally, cells must break down and recycle these molecules that are past their expiration date and make new ones.

To do this, they use autophagy, a word derived from the Greek for "self-eating".
Read 14 tweets
3 Mar
Hormesis is a fundamental concept in biology, and in health and disease.

Importantly, you can use hormesis deliberately to improve your own health and live longer.

What is hormesis?

Thread ๐Ÿ‘‡
Hormesis is a process in which exposure to a low dose of a toxin or stressor that is damaging at higher doses induces an adaptive beneficial effect on the cell or organism.

Hormesis is ubiquitous in living things.
Hormesis is fundamental to living organisms' ability to survive and thrive against the assaults of the environment

Hugo Schulz discovered hormesis in 1884 when he noted that yeast cells grew better in the presence of low doses of chemical disinfectants.
Read 11 tweets
1 Mar
Linoleic acid, the main component of seed oils, increases endogenous cannabinoids and promotes weight gain

At 8% of dietary energy, which is around the level Americans consume.

aocs.onlinelibrary.wiley.com/doi/full/10.10โ€ฆ
New study: Fat tissue from obese people has higher levels of omega-6 (seed oils) and higher levels of endogenous cannabinoids.

Omega-3 (fish oil) can normalize cannabinoid levels.

portlandpress.com/clinsci/articlโ€ฆ
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity

Hyperactivity of the cannabinoid system may be one mechanism

mdpi.com/2072-6643/8/3/โ€ฆ
Read 4 tweets

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