Certainly DeFazio is in no trouble. Dems can easily shore him up in redistricting. Axne is getting a much bluer seat in redistricting due to population changes.
Washington uses a bipartisan redistricting commission, so that ensures Kim Schrier gets a safe seat. Do the people working either party's committees know how redistricting works?
Laredo Congressman Henry Cuellar saw some of his crossover appeal dip this past cycle. Though he well outran Biden, he came just short of matching Clinton's margin and did a few points worse than Obama.
The Bexar portion shifted strongly leftward while Cuellar lost ground in rural areas. Bexar County (TX-28 pt)
2012 Pres: Romney 50-49%
2016 Pres: Clinton 49-47%
2020 House: Cuellar 54-43%
Even someone like Cuellar can't avoid the realignment.