The new thing on the right is calling the COVID vaccines "gene therapy." That's like saying horses are solar-powered because they eat plants. It's wordplay, the type of statement that is only "true" in a silly, useless, bad faith way.

Let's discuss.
/1
A viral vaccination works by putting something like the virus in your body so your immune system can learn to fight the virus. You can use a weakened or dead version of the virus, a specific part of the virus, or code for part of the virus.
/2

The vaccines carry code for the COVID spike protein. J&J carries it in DNA stuffed into a virus that can't replicate (Ad26), Moderna & Pfizer carry it in mRNA. Your cells read it and start making the spike protein.

None of them change your own genes.
/3 nytimes.com/interactive/20…
Here's the actual gene therapy products approved by FDA (notice, no COVID vaccines).

LUXTURNA, for a genetic form of retinal dystrophy, is real gene therapy. It delivers human genes to retinal cells.

The COVID vaccines have nothing like that.

/4

fda.gov/vaccines-blood…
"But but this SEC filing"—spare me. Yes, way back in 1993, the FDA said anything carrying genetic material is "gene therapy." Why? So companies can't evade regulation. It's intentionally broad.

In practice today, vaccines and gene therapy aren't even in the same FDA office.
/5
"But but this mRNA or Ad26 article says gene therapy"—yeah, it does, so what? The mRNA & Ad26 platforms can be used for human gene therapy. That is not what is in the COVID vaccines. They carry the SARS-CoV-2 spike protein code, and then they rapidly degrade.
/6
The irony is, researchers have been so keen on mRNA vaccines because they are so *limited* and presumably safer. It's sending in *just* the thing you want to send in (in our case, the spike protein code) and nothing else.

/end
ncbi.nlm.nih.gov/pmc/articles/P…
ncbi.nlm.nih.gov/pmc/articles/P…

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More from @MaxKennerly

2 Mar
Manchin's hero, Robert Byrd, believed presiding officer + 51 votes = cloture.

But if Manchin disagrees, he leaves @SenSchumer & @VP with no choice: end the "two-track" system and enforce Senate rules for debate.

There's a reason filibusters before 1972 usually failed.

/1
Talk back to the presiding officer? Fail (1837)

Poisoned eggnog? Somebody stepped out? Fail (1908)

Impugn another Senator? Fail (1948)

Need to pee? Trolled by a Senator with a drink? Fail (1957)

That's the real tradition of the filibuster.

getrevue.co/profile/maxken…

/2
.@Sen_JoeManchin talks about Robert Byrd as if he was a Republican obstructionist. The reason cloture is 3/5 now instead of 2/3 is because Dems, including Byrd, used the nuclear option in 1975.

Byrd's own view was chair + 51 votes = cloture.
getrevue.co/profile/maxken…
/3
Read 5 tweets
26 Feb
Reminder about all the supposed "norms" of the Senate: in 2001, when the Senate Parliamentarian "made it harder for the GOP to push President Bush's budget and tax cut proposals through the evenly divided body," Republicans simply fired him: washingtonpost.com/archive/politi…
I don't blame the Senate Parliamentarian, the "rules" of reconciliation are a joke.

In terms of "what now?" both options—VP Harris ruling otherwise or a standalone minimum wage bill—boil down entirely to whether 50 Dems would do it, i.e. Manchin & Sinema.
It's not really up to Harris. Sure, she can disregard the Parliamentarian—but she'll immediately face an appeal of her ruling. If she doesn't have 50 votes to back it up, it's an embarrassing defeat for no reason. The problems here are Manchin & Sinema.
Read 8 tweets
6 Feb
I want to pick up on the 'emergency relief' aspect, because this is yet another example of SCOTUS's "shadow docket" where they decide cases without full proceedings.

Unsurprisingly, they botched the facts of COVID restrictions in California.

/1
Gorsuch, joined by Thomas & Alito, couldn't figure out the rules for singing in movie productions, so inexplicably decided the issue in the church's favor.

Barrett, joined by Kavanaugh, held it was "unclear," but recognized the church bore the burden.

They're all wrong.

/2 ImageImageImage
As California pointed out in its brief, and the Ninth Circuit recognized, the film industry has onerous safety protocols that the church doesn't have and never said they'd adopt. It's not comparable.

And anyway they've also been prohibited from singing indoors since November.
/3 ImageImageImage
Read 4 tweets
6 Feb
Once again, Silver reveals that he has no idea what he's talking about. The J&J / Janssen vaccine uses a technology (adenoviral vector) that is entirely different from Moderna & Pfizer's (mRNA).

Let's talk for a second about what the FDA is doing and why.

/1
First, Silver's (and Yglesias's) whole argument is premised on FDA review of J&J's vaccine delaying distribution. That's questionable. J&J keeps a lot of this stuff confidential, but we know they've had delays and are not ready to distribute yet.

/2
At this very moment, the Biden admin is working to speed up J&J's production line. @aslavitt46 is on it. There is no benefit whatsoever in yelling at the FDA for doing its job to ensure the safety and efficacy of the vaccine.

/3 reuters.com/article/health… Image
Read 8 tweets
3 Feb
It's hardly surprising to see something thoughtless and outrageous from Greenwald & Dore, but I want to discuss one particular undercurrent of misogyny here, because it's widespread.

That is: if a woman is impolite to a man, the man is absolved of all responsibility.

/1
Let's assume Ted Cruz, a champion of deregulation who voted to rollback much of Dodd-Frank and is married to a managing director at Goldman Sachs, was sincere. 🙄

Is there a valid reason why Cruz's support for an investigation should depend on AOC's response? Of course not.

/2
For comparison, many members of the Obama admin had a hostile relationship with Warren over the CFPB's formation.

It would've been weird, gross, and pathetic if Obama had withdrawn support over that. But he's a grown man, so the work continued.

/3

Read 6 tweets
19 Jan
Yeah. The "power-sharing" is more "procedure-clarification" in lieu of a week pointlessly voting 50/50->Harris tie-breaker on each piece. Senate Dems still hold committee chairs, set calendars, and won't have bills blocked from the floor—which was McConnell's primary weapon.
An *excellent* question. McConnell would not do it in this document. He would do it later by violating a rule, getting rejected by the presiding officer, then appealing the ruling to the full Senate, which would vote his way, 50-50 plus VP tie-breaker.
If this sounds ridiculous—huh? McConnell agrees to Senate rules that he then reinterprets???—it's *exactly* what he did in April 2017 to eliminate filibusters for nominees, to move Gorsuch through: fas.org/sgp/crs/misc/R…

This time around, however, the deciding vote would be...
Read 4 tweets

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