Assessed #covid19 test positivity rates after 90 days in patients who tested positive previously— much less likely to have a positive result compared to those who tested negative previously.
2/ “Protection offered by prior infection was calculated as one minus the ratio of infection rate for positive patients divided by the infection rate for negative patients.”
3/ “Protection offered from prior infection was 81.8% (95% CI 76.6 to 85.8), and against symptomatic infection was 84.5% (95% CI 77.9 to 89.1). This protection increased over time.” #covid19
4/ “In this retrospective cohort, patients who initially tested positive for COVID-19 were less likely to be subsequently tested or test positive than those who initially tested negative during the same time period. Most reinfected patients were asymptomatic.”
5/ “In this study of patients in one health system, previous infection appears to offer high levels of protection against symptomatic infection, as well as severe disease, for at least 8 months.” #covid19
• • •
Missing some Tweet in this thread? You can try to
force a refresh
2/ They did weekly asymptomatic PCR testing here for 5 weeks
Limitations
-Community viral transmission at that time was also not very high
-Many of the activities here were done outdoors, where we know transmission risk is much lower #covid19
3/ "We observed a correspondence b/w the prevalence of infection per district & the number of new index-cases found in the same district. This finding supports that summer-schools did not act as super spreading hotspots, but rather reflected the underlying community transmission"
1/ If you are one of the many healthcare workers who have reached out to me privately about how your hospital won’t let you use N95 masks except during “aerosol generating procedures”— read this, because it’s BS.
2/ “Yet in recent months, Klompas and researchers in Israel have documented cases where workers using surgical masks and face shields became sick with Covid after providing routine patient care.”
3/ “A new wave of research now shows that several of those procedures were not the most hazardous. Recent studies have determined that a basic cough produces about 20 times more particles than intubation.”
Important paper from @BrighamWomens Dr. Klompas et al in @IDSAInfo — transmission of SARSCoV2 despite medical masks & eye protection (this is from our hospital); whole genome sequencing confirmation thanks to @MassDPH@lmadoff #covid19
2/ “We describe 3 instances of SARS-CoV-2 transmission despite medical masks and eye protection, including transmission despite the source person being masked, transmission despite the exposed person being masked, and transmission despite both parties being masked.” #covid19
3/ Again— what does this imply for poorly ventilated, crowded community settings where vulnerable frontline non-medical workers have been getting infected, are wearing *poorly fitting cloth masks* and are NOT yet vaccinated?? #covid19
South Africa & India pushed the WTO to suspend IP rights on #covid19 vaccines.
"Dozens of low-income and middle-income countries (LMICs) support the proposal. However, HICs including the UK, the USA, Canada, Norway, and the EU have rejected it outright"
2/ " saying that..."the IP system is required to incentivise new inventions of vaccines, diagnostics, and treatments, which might dry up in its absence. They dismiss the claim that IP is a barrier to access, and argue that equitable access can be achieved through..." #covid19
3/ "voluntary licensing, technology transfer arrangements, and the donor-funded COVAX Advance Market Commitment for vaccines."
The current patent system, while incentivizing innovation, doesn't incentivize equity for life-saving medicines/ vaccines. #covid19
1/ Some have asked why fully vaccinated can only visit with “a single household” of unvaccinated people who are low risk.
We still have high rates of circulating virus in community. Unvaccinated low risk people can still get sick/ pass on virus more than those who are vaccinated
2/ By having multiple unvaccinated households gathering w/ vaccinated person(s), you are then again creating a higher risk setup for disease transmission
3/ Also, vaccinated people can also still pass virus onwards, although less so than those who are unvaccinated.
This is why CDC is being very specific to say small gatherings with *low risk* unvaccinated has a cost/benefit in favor of social connection given low chance of harm
Spoke w @HarveyLevinTMZ@charleslat@TMZLive regarding the role of athletes & public figures in addressing vaccine hesitancy, the focus here being on Lebron James’ recent decision to keep his vaccination decision private. #covid19 (part of conversation here)
2/ I recounted the story of my recent Lyft driver who asked about vaccines and said he didn’t trust politicians or the pharmaceutical industry. But we still had a productive conversation. And it ended w/ him a little closer to getting vaccinated. #covid19
3/ This brings up an interesting ethical dilemma re the role of public figures like athletes or movie stars etc who have significant influence - & who people may actually end up trusting or following more than politicians & others who have been politicized during the epidemic