I would take a deep breath and wait for AZ to release primary efficacy results to see if there is any meaningful difference from the prespecified interim analysis reported yesterday. Usually there will be some differences. It happened with the other vaccines also.
https://twitter.com/drericding/status/1374321946062622723
It is quite extraordinary for a DSMB to express concern over release. Not sure if there was a misunderstanding when the DSMB asked AZ to release results, if it specifically told them to wait and release Primary Analysis or not.
Again unless the difference is meaningful not sure what to make of this other than it's pretty strange. Never happened to me in any of the trials that I have been involved with.
Generally in trials that Ive been involved with, DSMBs review data & recommend release when they see endpoints are met. They don't often specify exactly what to release. There's discretion to study team. Maybe they expected AZ to release primary analysis but AZ released interim?
I remember when the Moderna vaccine FDA briefing document came outc @DrEricDing sent a tweet showing that their data did change from the interim analysis that was released earlier and the final analysis reported in guidance document. Not able to locate the tweet. 
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