"SARS-CoV-2 was remarkably well adapted to humans from its first appearance, yet poorly adapted to bat infection, the natural reservoirs for SARS-r-CoVs, with little evidence for gaining its human adaptation through natural recombination."
Aka "evidence".
link.springer.com/article/10.100…
Aka "evidence".
link.springer.com/article/10.100…
"SARS-CoV-2′s receptor binding domain (RBD) appears to be highly optimized for binding to human ACE2"
Aka "evidence".
Aka "evidence".
"The combination of binding strength, human and mouse peptide mimicry, as well as high adaptation for human infection and transmission from the earliest strains might suggest the use of humanized mice for the development of SARS-CoV-2 in a laboratory environment."
Daszak *2019*:
Daszak *2019*:
This is a great illustration of the various ways the virus could have infected humans. Based on everything that is known about what the Wuhan lab was up to, as well as the lack of intermediate host and low binding of the virus in bats, the mouse theory seems the most likely one.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
