1/
Attending: “But never anticoagulation for an intracranial dissection!”

Me as a resident: “Of course. Totally!”

Also me ⬇️: [googling “where do the internal carotid arteries and vertebral arteries become intracranial?”]

Feel familiar? A #tweetorial @MedTweetorials
2/
With the TREAT-CAD trial, lots of talk about dissection treatment. Whether your team anti-platelets or team anticoagulation (🙋🏻 Must. Give. Heparin (@MGHNeurology) 4 ever. I know you feel this, @namorris!) consideration about the location of dissection is possibly important.
3/
Also, regardless of your team… TREAT-CAD was not able to demonstrate non-inferiority of ASA, just saying.

Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiorit… pubmed.ncbi.nlm.nih.gov/33765420/
4/
K, back to the question.
So, when do the verts become intracranial? This is fairly straight forward -- as it passes through the transverse foramen of C1 marking the transition between V3 and V4 segments.
5/
The carotids are more complicated. The most commonly used naming system was described by Alain Bouthillier in 1996.
Segments of the Internal Carotid Artery: A New Classification …demic-oup-com.proxy.library.emory.edu/neurosurgery/a…
6/
In reading this I developed an appreciation for the incredible anatomical effort that went into describing these segments. The illustrations in this manuscript are INCREDIBLE

C1-cervical, C2-Petrous, C3- Lacerum, C4-Cavernous, C5-Clinoid, C6-Ophthalmic, C7-Communicating
7/
Most authors consider the carotid intracranial as it transitions from the cervical segment into the carotid canal in the C2-petrous segment. HOWEVER, the carotid is not *intradural* until it traverses the distal dural ring at the end of the clinoid segment:
8/
After passing the distal dural ring, extension of dissection could result in subarachnoid hemorrhage.

Note: While SAH may not be a complication of more proximal dissection, a carotid-cavernous fistula could result from a subadventitial dissection in the C4-Cavernous seg.😱
9/
Does SAH develop after the initial injury though and is it really not safe to anticoagulation a patient with an intracranial dissection?

The answer is it probably doesn’t happen often, and it’s probably safe.
10/
In one large case series of 80 patients with intracranial dissection, with no radiographic or clinical concern for presenting SAH, no cases of SAH were observed despite treatment with anticoagulation.

ahajournals.org/doi/10.1161/st…
11/
However, I still often want to know.

Many images exist that demonstrate the segments of the carotid/verts. But, none that I found had them in as reformatted CTA MIPS next to the bony segments, which is what I wanted.

So, I made some for the #acuteneurologysurvivalguide!
12/
If you want to do more reading, both radiopaedia.org and Neuroangio.org have excellent articles. Highly recommend!

#neurotwitter #acuteneurologysurvivalguide #endneurophobia #MedEd

Thoughts? @namorrismd @AaronLBerkowitz @Capt_Ammonia @sauravmed @rwregen

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More from @caseyalbin

26 Mar
1/
Your patient that is “over breathing” the vent may still be dead by brain criteria.

A #tweetorial #medtweetorial for providers in #criticalcare #EM #neuro #neurocriticalcare. @MedTweetorials
2/
First and foremost, let’s be clear that to be dead by brain criteria, the patient must have cessation of ALL brain function *INCLUDING absence of respiratory drive.*

Thinking "But... I thought you just said...."?
3/
The contradiction here lies in that ventilators are sometimes too sensitive.
Read 13 tweets
18 Feb
1/ Alright, #Neurotwitter, the votes for today’s #neuroDDxThursday were overwhelmingly in favor of multiple cranial neuropathies!

Thought about one slide, but this needs a #tweetorial! So that you aren't 😬😬😬 when confronted with this:

#MedEd #FOAMed @MedTweetorials
2/
Reminder: The 12 cranial nerve nuclei are located in the brainstem, and if you have trouble remembering where they are, welcome to the club. Here’s a reminder! Will post the medulla section Monday, stay tuned.
3/
We’ll move from central to peripheral etiologies.

The brainstem is like Times Square in NYC- so much going on in a very small space.

A small insult can easily cause damage to multiple cranial nerves. amiright, #stroketwitter?
Read 15 tweets

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