According to Konstantin Chumakov (Associstr zdirectir for vaccine research at FDA) this method generally produces a weak response from the immune system, which is why so called adjuvants are used. But an adjuvant can produce serious side effects which are not well understood.
In addition, the Vector vaccine is a one dose vaccine, a surprising decision for this type of vaccine.
The third Russian vaccine (inactivated virus) is made by the Chumakov Center (the former Polio Institute) named after Mikhail Chumakov (Konstantin’s father), who was one of
USSR’s most famous virologists (responsible for mass vaccination for polio). This institute (unlike Vector) has a lot of experience in making thus kind of vaccine & Konstantin Chumakov expects it to be Russia’s most reliable one. But the distrust created by the secrecy, false
claims and most of all, distrust of Russia’s mass production of drugs, where adulteration is common (Latynina quotes Professor Preobrazhensky from “Heart of a Dog” - “Don’t drink Soviet vodka. You have no idea what they have put in it”) will mean that even this vaccine is
unlikely to be the silver bullet Russia needs.

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More from @akoz33

9 Apr
Andrei Illarionov "Why Biden's phone call has increased the risk of another Putin offensive". My translation (with some cuts). Part I.
Perhaps dear readers you may not have noticed it yet, but astute political analysts (henceforth known as APA), who had previously announced the beginning of a “new cold war” by the “second Churchill”, have now have announced
the end of the more than seven year Russian-Ukrainian war, and as a result : " On April 2, 2021, the Russian-Ukrainian war ended in an unconditional political defeat for the Russian Federation."
Read 36 tweets
9 Apr
Russia has now demanded that Slovakia returns the Sputnik V vaccine it has supplied to it. You may ask:"why?"
It's because the Slovaks noticed (as I told you here earlier ) that the vaccine is not identical to the one that was tested and described in
Lancet. It's not a joke. Russia really sent to Slovakia "nobody knowswhat" (here is the scene from Heart of a Dog, mentioned by Latynina a long a time ago in connection with the production of Russian vaccine, in which professor Preobrazhensky advises Dr Bormenthal not to drink
Soviet vodka because "God knows what they put into it. What came to their heads..."
Read 4 tweets
9 Apr
Russia’s former President and Prime Minister, currently deputy head of the Security Council Dmitri Medvedev has announced on Instagram that he is going to run for President in 2024. Medvedev published a photo of himself having lunch with Obama during their presidency. He wrote
“Russia has travelled a difficult route, but it has not gotten rid of the curse of the 90s. For the past 20 years have been ruled by scoundrels and ineffective managers. All this time they have been pulling Russia apart and leading our people to poverty.
The country is tired of amateurs and political crooks. The economic situation is not encouraging. The ruble has barely grown, the real incomes of Russians have increased only slightly, Russia came close to the fate of a rogue country.
Read 5 tweets
7 Apr
It’s interesting to note the state of the covid epidemic in Chile. Look at the rapid rise of infections (though not so much in deaths). Now, the point is that Chile is one of the world leaders in vaccination. But unlike the others, Israel, UK, US, it has been relying for 90% of ImageImage
its vaccinations on the Chinese Sinovac vaccine. The effectiveness of this vaccine is disputed but the worst results point to it being just over 50% effective, barely enough for approval in the US. UAE is also using this vaccine although in lesser proportion than Chile and the
results don’t look great either but there is visible improvement. Why would a vaccine based on “true and tried” over 100 years old technology be so ineffective? Well, to some extent it seems so because the new mRNA vaccines and the adenovirus based vector vaccines have proved Image
Read 5 tweets
4 Apr
One of the greatest achievements of 21st century science was due to this American-French alliance (the only time two women shared a Nobel prize). But there were other aspects of the story of the discovery of CRISPR-CAS that are worthy of note. Francisco Mojica was the first
researcher who discovered and named CRISPR (a family of DNA sequences used by some bacteria to defend themselves from viruses) but his breakthrough paper was rejected by 4 major scientific journals before finally being published (after 2 years) by a less prestigious one. And
the same thing happened when in 2012 Lithuanian biochemist Virginijus Šikšnys submitted his paper on programmable DNA cleavage, the same idea that gave Charpentier and Doudna their Nobel prize. His work was rejected and published after a long delay. Charpentier and Doudna
Read 4 tweets
4 Apr
Latynina on the Russian military moves against Ukraine:
This leads us to another topic - to the concentration of troops on the Ukrainian border and a bunch of videos in the social media of movement of Russian armour. e "potentially imminent crisis".
And an increase in the level of alert of the European command of the US Armed Forces, which has been raised this level to "potentially imminent crisis".
And everyone began to play the game of guess whether there will be a new invasion of Ukraine or not. Frankly, I find it somehow hard to imagine that Putin will order an invasion while he is negotiating with Macron and Merkel about exporting to the west the Sputnik V vaccine.
Read 31 tweets

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