Thread by @bansisharma

1. J&J Vaccine Pause

Considering the volumes of commentary disagreeing with the decision to pause J&J Covid-19 vaccine administration because of a "one in a million" chance of developing blood clots, here is my speculative take on the real reason for the prudent pause.

2. The rare blood clots seen in six women within two weeks of having been given J&J Covid-19 vaccine have an anomalous nature. These blood clots were accompanied by low platelet counts.

3. It is my understanding (I am not a doctor) that this is quite anomalous, because low platelet counts usually don't cause blood clots. They are more likely to cause bleeding, because they inhibit blood-clotting.

4. Consequently, the usual treatment for blood-clotting cannot be used in these cases. I believe that is the really scary part of these anomalous cases, not the "one in a million" cases of blood-clots themselves.

5. It is understandable that if a drug causes a condition that doctors don't understand well and don't have good, or maybe any, treatment options for, we would take a pause, especially since other vaccines (Pfizer and Moderna) that do not cause such complications are available.

6. Keep in mind the mechanism of action for Pfizer and Moderna Covid-19 vaccines (mRNA based) is different from that of J&J and AstaZeneca vaccines (adenovirus based). Any issues discovered with one type of vaccines should not be assumed to have implications for the other type.

7. These are complicated matters that require a patient and detailed explanation than our sick media is capable of providing at the moment. And there is no cure for what ails our media whose business model now is to profit by causing panic, racial strife, and rioting.

The End

On Tuesday, Peter Marks, head of the FDA center that regulates vaccines, said on a call with reporters that there have been no cases of CVST with thrombocytopenia with the Pfizer/BioNTech and Moderna vaccines, indicating that the side effect is not occurring with those vaccines.

This article does a good job of explaining the issue of rare blood clots in patients treated with AstraZeneca and J&J Covid-19 vaccines.
statnews.com/2021/04/13/res…