Thread by @jmteakell

Excellent #KIDNEYcon session by ⁦@criticalbeansmd⁩ about MAP and other perfusion pressures.
👉 Blood pressure is not the same as blood FLOW.

Under normal conditions, pulse pressure wave precedes flow volume wave. #KIDNEYcon

In sepsis, vasodilation can lead to decreased speed of pressure wave and increased speed of flow wave.
#KIDNEYcon

Hence increasing MAP as isolated target, may not be reliable index of flow 👉 organ perfusion.
#KIDNEYcon

Factors affecting blood flow
#KIDNEYcon

But don't forget about the venous pressure and consequences of volume overload.
#KIDNEYcon

A state often misinterpreted as 'total body overloaded, but intravascular depleted' ... resulting in more volume administered 🚫