Hello all! @NeuroErinPhD here - I’m thrilled to be curating the feed this week. Here's an intro thread on my journey in science…🧵(1/7)
I'm a postdoctoral researcher in neuroscience at University College Cork, Ireland @AnatNeuroUCC. My research in the lab of Dr. Olivia O'Leary focuses on sex differences in stress-related psychiatric illness and developing novel therapeutic targets (2/7) The quad at University Coll...
So how did an American neuroscientist get a job in Cork? The power of #sciencetwitter, of course! I saw @oliviafoleary's postdoc ad mentioning stress, sex differences, & adolescence...and I had to reach out! 3 years later, I’m living in Cork doing science with awesome people. 3/7 My advisor, Dr. Olivia O'Le...
I started my training in neuroscience as an undergrad at Tulane University @TulaneNeuro. I was fortunate to get loads of hands-on experience in the lab of Dr. Laura Schrader working on a project studying the acute stress response in the hippocampus. (4/7) Image
I went on to get my PhD at University of Virginia @uvaneuro with Dr. Emilie Rissman, where I studied the neurobehavioral impact of endocrine disruptors (chemicals in our environment that mimic the actions of hormones) during development (5/7) My PhD advisor, Dr. Emilie ...
Midway through my PhD, the lab relocated to NC State @NCStateBioSci @NCState_CHHE, where I met a ton of awesome neuroendocrinologists! (BTW, happy to answer any questions about moving universities in the middle of a PhD. It was an...interesting experience) (6 of 7)
My fantastic mentors and colleagues over the years have emphasized the importance of including sex as a biological variable (#SABV). I'll be highlighting many SABV researchers (not just in neuroscience) this week - Looking forward to sharing some great science with y'all!

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More from @realscientists

7 May
Here's podcast episode to check out! The @EndocrinePod featuring the fantastic, @walkerdm79 (with a new lab at OHSU @walkerlabohsu) and hosted by @superchiasmatic, a neuroscientist and #SciComm-er with a super handle🦸‍♀️
Thread on her recent publication in Biological Psychiatry
Read 4 tweets
7 May
.@LastWeekTonight did a great piece on bias in medicine in 2019 that features an excerpt of an interview with Larry Cahill from a 60 Minutes story ("Sex Matters" in 2014).
Larry Cahill wrote a great response to Gina Rippon's "The Gendered Brain" -- a tweet from the amazing @Docbecca explains...
She also lists some more researchers studying sex differences #SABVscientists
Read 4 tweets
6 May
At the start of lockdown last year, I downloaded #TikTok and I’ve been hooked ever since! My own videos are a mix of “life in the lab”, some singing & music, and a generous helping of silliness 😁
vm.tiktok.com/ZMeqjhy3c/
I’ve really enjoyed being part of the science community there over the past year — here are a few of the amazing scientist creators on TikTok ⤵️
big_science_energy! She also streams on Twitch
vm.tiktok.com/ZMeqjRwok/
Read 16 tweets
5 May
Thrilled to see research on #Covid19 considering sex and gender differences! I'll link a few more articles underneath 👇
Great infographic from @CIHRIGH on including sex and gender in Covid-19 research
cihr-irsc.gc.ca/e/documents/ig…
Read 8 tweets
13 Apr
Ok so I had a rather hectic evening, but now let's talk about simulating proteins!
First of all, what's a protein?

Protein's are large biological molecules that are responsible for a myriad of different processes in living things. Feel hungry? In pain? Taste something sweet? Feeling an emotion? All of these things are controlled by a vast array of proteins!
Proteins are amazing! Each one is highly specialised to carry out a specific task, what's incredible is that all proteins are made from the same building blocks called amino acids (AAs).

en.wikipedia.org/wiki/Amino_acid
Read 19 tweets
13 Apr
Great question!

Yes we can usually determine if a calculation will be expensive by assessing a number of parameters ⬇️
In the context of QM calculations we have to assess whether the level of theory we are using is appropriate. Perhaps we could use a cheaper ab initio, semi-empirical, or DFT method. The choice depends on the question and system!

Also: basis sets
Without going into too much detail, basis sets help to describe the shape and behaviour of electrons around certain atoms. We can make them really detailed (i.e. model every electron) or just model the important ones (ones involved in bonding etc)

en.wikipedia.org/wiki/Basis_set…
Read 6 tweets

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