1/ A few #COVID19 vaccine updates for Ontario:

The pace of vaccination is picking up again.

>130000 vaccines were administered May 4, and >133000 today so far.

>40% of adults in ON have received a 1st dose.

Some thoughts about the past & future weeks👇 Image
2/ People came out in droves for AstraZeneca when the age limit dropped to 40. We had a lot of AZ in the freezer at that time & now there is not much left.

(Much has been said about AZ since then. I am happy for people who received it)
3/ AstraZeneca administered via ~1400 pharmacies & primary care (family doctors & nurse practitioners) pushed our daily vaccine rate to over 130K/day. The pace slowly dropped as supply diminished.

AZ use significantly dropped yesterday & today, likely driven by public discourse.
4/ The fast pace of overall vaccination yesterday & today is largely driven by Pfizer & to a lesser extent Moderna, through:

1) Mass vaccine clinics
2) Pop-up & mobile clinics

This is an impressive pace, especially given the lower rates of AZ administered via pharmacies.
5/ We are getting a ton of Pfizer this month & beyond. Moderna is also starting to pick up.

Pharmacies are starting to administer Pfizer & will expand. Primary care is administering AstraZeneca & will likely expand their use of Moderna as well.

Source: bit.ly/2RrFblt Image
6/ So the plan is to expand the pace of vaccination (with greater Pfizer access) through mass vaccine clinics & pop-up/mobile clinics.

The pace of vaccination will further increase as:

1) More pharmacies start to administer Pfizer
2) Primary care's role expands significantly
7/ Vaccines in Freezers? Nope.

Here are the vaccines allocated & administered by each province.

Data is from May 4th, right before the big Pfizer shipment...Ontario had administered >95% of all vaccines (highest in the country).

We have a lot to administer now to keep up. Image
8/ Equity (Part 1):

In early April we were seeing inequity of vaccine administration...more vaccines administered in less impacted neighbourhoods.

But through much of April, 25% of vaccines were allocated to "hot spots" & we can see many of these inequities ironed out.👇👇👇 Image
9/ Equity (Part 2):

For the next 2 weeks, ON is allocating 50% of vaccines to 114 highly impacted postal codes, with everyone 18+ years eligible.

But even with this plan, ensuring equitable allocation & administration will be an ongoing effort.

Source: bit.ly/2SumdLD ImageImageImage
10/ Equity (Part 3)

There are many teams working hard to get the right needles into the right arms.

Great example below by @joe_cressy. This involves community engagement & lowering as many barriers to vaccination as possible in hot spots.


11/ Areas for improvement in Ontario's vaccine rollout:

*Expansion of primary care involvement, province-wide
*Cumbersome sign-up system
*Expansion of Pfizer in pharmacies
*More frequent communication & better transparency
12/ Also, just because various groups are eligible to sign up, it does not mean they will be vaccinated imminently.

In May we get ~800K doses of Pfizer per week & ~800K doses of Moderna total. That's a lot of vaccine but not enough for all of us.

It will take a bit more time. Image
13/ 2nd doses:

It is likely (not guaranteed) that many will receive 2nd doses before the 4 month mark due to greater supply.

Also, we can likely start to vaccinate the 12-16 year age group perhaps sometime in the early summer, well before school.

14/ **Total speculation here** For those who received a 1st dose of AstraZeneca, there may be an option to receive a 2nd dose of Pfizer given 1) stable/large supply of Pfizer, less so with AZ, 2) pending results of COM-COV study in the UK.

Stay tuned.

comcovstudy.org.uk/home Image
15/ I hope this clarifies a few questions that come up from time to time.

There is still room to improve but some aspects are going rather well.

We'll get this done.

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More from @BogochIsaac

6 May
1/ Ontario #COVID19 vaccine update (Take 2 - after twitter hack/drama):

Ontario has vaccinated >130000 people per day May 4, 5 & on track for this today too.

Over 40% of adults in the province have received at least 1 dose.

Some details on past few days & next few weeks 👇 Image
2/ We doled out a ton of AstraZeneca when eligibility dropped from 55 to 40 yrs, but then ⬇️ supply led to ⬇️ pace of AZ vaccination.

Currently there is very little AZ administered this week following recent public discourse.

I am happy for those who received this vaccine.
3/ Equity of vaccine administration was an issue earlier in April. There is ongoing prioritization of supply to heavily impacted neighbourhoods & it's working.

This graph was when 25% of vax supply went to hot spots.

Now hot spots get 50% of supply for the next 2 weeks. Image
Read 11 tweets
1 May
1. "Health Minister Patty Hajdu says her government embraces the concept of 'vaccine passports' & will come up with a form of certification to allow vaccinated Canadians to travel internationally."

Smart move & good to be proactive.

bit.ly/3eNTusr by @peterzimonjic
2/ There are a growing number of countries requiring proof of #COVID19 vaccination for travel...18 are currently listed here.

Also the EU just announced they would be open to vaccinated travellers from the USA this summer.

3/ #COVID19 vaccine certification for travel will likely be a global norm:

Read 6 tweets
28 Apr
1/ A few points to clarify a few points...

These vaccines are really really good, but not perfect.

One dose of a vaccine provides excellent protection against #COVID19 infection, but of course 2 doses provide more protection.
2/ NACI outlines protection after 1 dose of a vaccine in their recent document:

"Most importantly, these studies show one dose of the Pfizer-BioNTech & AstraZeneca vaccines are
approximately 80% effective against hospitalization..."

Details: tinyurl.com/saby9kma
3/ Here is some of the data backing up NACI's statement above, but from a clinical trial.

This graph below is with Pfizer...look at how people start to gain protection ~12-14 days after their 1st dose (red line).

Pretty impressive.

Link: bit.ly/3aO00OR
Read 8 tweets
23 Apr
1. Ontario administered >125000 vaccines today.
2. Todays ~125K is not the final count, there are still a couple of hours left.

Yesterday ON vaccinated ~134K (that's 0.91% of ON population in a day).

By comparison, yesterday the USA vaccinated ~3.1 million (0.94% of USA population in a day).

We are catching up.
3. The provinces are all pretty comparable in administering vaccines delivered to them, with a range between 71% to 86% in arms.

Ontario has administered 81% of vaccines delivered to the province. Very much aligned with the others.

Source: bit.ly/3sJCuZA
Read 5 tweets
23 Apr
1. Ontario has prioritized pregnant individuals for #COVID19 vaccination (see below).

Really glad to see this happen - it's the right move.

(Expecting to hear further sign-up details from other Public Health Units shortly)

@TaliBogler *I think they mean "highest risk" below.
Read 6 tweets
15 Apr
A few points to clarify vaccine distribution in Ontario.

1. We get ~400K doses of Pfizer weekly. It shows up like clockwork. It gets distributed throughout the province in ~1-2 days & there is very little at the end of the week. This is administered at mass vaccine clinics.
2. We get several hundred thousand doses of Moderna every 2 weeks. Also rapidly shipped to locations in the province. For various reasons, Moderna shipments are occasionally delayed. There is very little Moderna in freezers at the end of the 2 weeks.
3. We have infrequent large boluses of AstraZeneca. This is administered by primary care in 6 Public Health Units, and by ~1400 pharmacies throughout the province.

It is available to anyone 55 years of age and older.
Read 17 tweets

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