A recent study shows that a single dose of AstraZeneca’s vaccine in HCWs previously infected with SARS-CoV-2 serves as an effective immune booster up to at least 11 months post infection and effectively neutralizes WT, and SARS-CoV-2 variants of concern P.1, B.1.1.7, AND B.1.351!
Researchers here compared spike-specific IgG and pseudo-neutralizing spike-ACE2 blocking antibodies against SARS-CoV-2 wild type and variants B.1.1.7, B.1.351, and P.1 following two doses of Pfizer’s vaccine and a single dose of AstraZeneca’s vaccine in 232 healthcare workers
with and without a previous SARS-CoV-2 infection. What they found were that post-vaccine levels of spike-specific IgG AND neutralizing antibodies against the SARS-CoV-2 wild type and all three variants of concern were similar OR indeed higher in participants receiving a single 
dose of AstraZeneca’s vaccine post SARS-CoV-2 infection (both < 11 months post infection (n=37) and 11 months infection (n=46)) compared to participants who received two doses of Pfizer’s vaccine (n=149). Study can be found here: medrxiv.org/content/10.110…
If you were concerned about AstraZeneca’s effectiveness against certain variants of concern, I highly recommend viewing this study. ALSO, this does NOT mean it’s only effective for 11 months. I see the confusion. It’s AT LEAST 11 months. This was the time frame of the study.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
