Thread by @DRTomlinsonEP

Catch me if you can: Superspreading of SARS-CoV-2
Highly readable: recommended.
h/t @microlabdoc cell.com/trends/microbi…

Theoretical mechanisms - differential glycosylation: 'SARS-CoV-2 produced in individuals with distinct blood groups may differ in their glycosylation patterns, which could impact the binding and susceptibility of SARS-CoV-2 in respiratory epithelium and subsequent transmission'

And just for you @MicrobiomDigest: 'These observations suggest that nasal microbiome communities can influence efficient airborne transmission of respiratory viruses'.

Physical factors driving transmission: 'in superspreader events, long-range transmission is likely to mediate a large proportion of the cases'

'Persistence & concentration of SARS-CoV-2 in virus-laden aerosols is critical for long-range transmission in a superspreader event.'

And look! My good friend the Goldberg drum even gets a mention @LazarusLong13 @akm5376
#COVIDisAirborne

And obv: 'increased ventilation & reduced capacity in indoor spaces decreases transmission of SARS-CoV-2. Thus, until the host specifics of a superspreader are known, basic NPIs like increased vent'n & air exchange rates may alter the consequences of a superspreading event.'

Too many unknowns for comfort: a snippet

👏👏 @Lakdawala_Lab @TheMenacheryLab