Thread by @KhurramMstf

In the 1st multi-centre study from England, we identified factors that increase the likelihood of children needing #CPR in #PedsICU. Children from Black & Asian ethnic backgrounds were more likely to require CPR
@JAHA_AHA
1/10
@Picstato @rgfeltbower @RameshK49951542 @BarneyUoB

Cardiopulmonary arrests are a major contributor to mortality and morbidity in #PedsICU. Understanding the epidemiology and risk factors for #CPR may inform quality improvement #QI initiatives. ahajournals.org/doi/10.1161/JA…
2/10

We aimed to identify incidence and factors associated with variability of incidence of #CPR in #PedsICU by performing a retrospective cohort analysis on data from #PICANet with @PICSTato @rgfeltbower @RameshK49951542 @BarneyUoB
3/10

#PICANet picanet.org.uk is a treasure of quality data from all #pedsicu admissions in UK and Ireland. Produces annual reports for @NHSengland and huge resource for @NIHRresearch and #QI projects. Ideally placed to help us answer our question.
4/10

This is the first multi-centre study from England reporting data on >1500 children who received #CPR after admission to 23 #PedsICU over a 5‐year period.
5/10

Cumulative incidence of #CPR was 2.2% for 68,114 admissions with an incidence rate of 4.9 episodes/1000 bed days, accounting for about 400 episodes of #CPR every year in England.
#Pedsicu
6/10

In unadjusted analyses, the following were associated with increased odds of receiving #CPR
•Cardiovascular diagnosis ⬆️2.3x
•age <1 year ⬆️1.8x
For every day longer in PICU, the odds of needing #CPR increased 13% ⬆️

7/10

We also found higher odds of #CPR associated with a
•Having had a cardiac arrest before admission to #pedsicu ⬆️20x
•Existing cardiac condition admitted to a non-cardiac designated #PedsICU ⬆️2.8x
8/10

A really important finding was that children from Black and Asian ethnic backgrounds were ⬆️1.7x and ⬆️1.5x more likely to receive #CPR in #PedsICU than White children. These are unadjusted risks and should inform further research.
9/10

An association between mortality after discharge from #PedsICU and ethnicity was previously reported by #PICANet, and our findings support the need for important research to explore higher risks related to ethnicity and any racial disparity.
10/10

Very grateful to all co-authors for their support and input @Picstato @rgfeltbower @RameshK49951542 @BarneyUoB. This has been a tremendous learning experience. Motivated to continue my research journey in #PedsICU