1.THREAD on latest Sanger data on B.1.617.2 (new variant of concern).
Remember Sanger use all sequenced cases for England (about 50% all cases) and remove data from travellers and surge testing - so approx community cases.
2.Continued rapid increase of B.1.617.2 (a so-called "India" variant) to week ending 8 May. Other variants not doing much.
But B.1.617.2 now almost 30% of sequenced cases in England (!).
3.Regionally, it almost dominant now in North West and getting there (but more slowly) in London.
High proportions in SW and SE, but overall cases here v low. Need to keep an eye on the Midlands & East of England.
4.Looking at absolute weekly sequenced numbers, the rapid increase of B.1.617.2 compared to other variants (including its sibling B.1.617.1) is obvious.
5.This data might still over-represent B.1.617.2 & there are ways it is could increase rapidly without being more transmissible.
But I think the simplest explanation is that it is more transmissbile & we are right to be worried. Precautionary principle suggests action now. /END
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2 COG data is not entirely representative because it over-represents surge and traveller cases.
Sanger data removes traveller and surge cases to try to get a picture of community transmission, but Sanger only updates once a week.
What if we compare the two?
3 This compares the number of sequenced tests of B.1.617.2 that appear in COG (black) and Sanger (blue).
Over time there is much more overlap between the two showing that community cases are growing and that COG is becoming more representative of community cases (Sanger).
2. Hancock apparently said the "vast majority" of unvaccinated patients were eligible. I don't know what "vast majority" of 12 is, but let's say it's 11.
About 95% of over 50s have had 1 dose and about 90% of over 70s have had 2 doses in England.
3. Eligible is over 40s and health care workers - so can't say too much *precise* about vax efficacy without knowing more (inc exposure).
We also don't know which variant but >70% of cases in Bolton from recent Sanger data were new variant (B.1.617.2).
SHORT THREAD:
I was on Sky News earlier where I explained why I thought test 4 (new variant test) for the next stage of the roadmap had not been met, because of B.1.617.2 (the so called "Indian" variant of concern). 1/5
I then also said what I, personally, thought that meant for next steps.
Added to these must be much more support for local teams to beat outbreaks *and* proper financial & practical support for those who test positive & contacts. Once in place, could enable safer opening. 2/5
@markaustintv pointed out that people would be shouting at the telly hearing me suggest delaying Monday's opening... this is what I said about that. 3/5
The govt set out 4 tests for proceeding each stage of the roadmap. Tests 1 & 2 relate to vaccination, test 3 is hospitals in no danger of being overwhelmed and test 4 is that there are no new variant concerns.
Test 1-3 have been (easily) met, but I don't think Test 4 has. 2/18
Last Friday, Public Health England designated B.1.617.2 (an "Indian" variant) as a variant of concern because of worries that it was more transmissible than B.1.1.7 ("Kent") and cos we didn't know much about its response to vaccines.