Estimated excess mortality during the pandemic far outstripped officially reported Covid deaths in most countries. However, many countries, and in particular low- and middle- income countries, don’t estimate excess deaths econ.st/33VduV6 1/
Statistical modelling by @TheEconomist suggests the Covid death toll is between 7.1m and 12.7m. That means the official death toll represents, at best, about half the true toll and, at worst, a quarter of it. 2/
Most uncounted Covid deaths occurred in LMICs. In OECD countries, the true death toll was estimated to be 1.2 times the official number; in parts of Africa, it was estimated to be 14 times the official number. 3/
Estimates are no substitute for real data. Only better tracking of mortality data can provide the data necessary to inform and focus our efforts to prevent deaths — due to COVID-19 and other causes 4/

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More from @DrTomFrieden

14 May
A Tale of Two Pandemics

The pandemic won’t be over until most of the world is vaccinated, but access is a HUGE challenge.

Globally, we must scale up manufacturing and vaccinate the 50M health workers & 1B people over 60. In the US, we must proactively reach the unreached. 1/
Vaccine inequity is a serious problem, both ethically and epidemiologically. It increases the risk that dangerous variants will emerge. Wealthy countries have excess vaccines while lower and middle-income countries go without. 2/ Image
The reality is that global vaccine supply will lag the need for at least a year. Open IP is a step, but we need much more—transfer of vaccine technology and hubs for production. We can also be more strategic in use of the vaccine that is available. 3/
Read 23 tweets
13 May
The Last Pandemic?

The Covid pandemic has killed 3+ million people and driven 115M people into extreme poverty. It will cost the world $22 trillion by 2025. And it didn't have to happen.

A new report could be pivotal in efforts to prevent the next pandemic. 1/
The Independent Panel for Pandemic Preparedness and Response (@TheIndPanel) was created last year by @WHO to ensure the world is better able to address health threats such as Covid. They released a sweeping new report. nyti.ms/2RS1TTV 2/
Because the recommendations detailed in the report are so important, I’m going to highlight some of them in the hope that the story of Covid isn’t repeated. Read the report here: bit.ly/3w6nEyr 3/
Read 24 tweets
30 Apr
Globally, the end of the pandemic isn't near.

More than a million lives depend on improving our response quickly.

Don’t be blinded by the light at the end of the tunnel. There isn't enough vaccine and the virus is gathering strength & speed. Global cooperation is crucial. 1/
India’s surge is a reminder that the virus is learning about and adapting to us faster than we're learning and adapting to it. Covid, fueled by variants, is an ongoing & increasing risk. The pandemic is more severe than ever—more transmissible, more deadly, more human fatigue. 2/ Image
Dazzling scientific progress resulted in Covid vaccines that are more effective than many experts dared to hope. But although Israel, the UK, and, soon, the US will have a new reality with the virus largely tamed by vaccines, global vaccination lags badly. 3/ Image
Read 21 tweets
16 Apr
Benefits, Risks, and Future of Vaccines and the Pandemic

Our vaccine safety monitoring system works. Reports of blood clots led to quick investigation, quick action, and transparency about what is known, not known and next steps. Vaccines remain our way out of the pandemic. 1/14
Global collaboration has been critical throughout the pandemic. Public health and medical experts around the world are collaborating to determine whether the events associated with AstraZenenca vaccine are the same as these events which may be associated with the J&J shot. 2/14
Tech transfer is crucial. The pandemic is the world’s most important problem. mRNA technology is our best solution. Create high-quality manufacturing platforms and hubs around the world to improve vaccine access. mRNA technology is an insurance policy against the pandemic. 3/14
Read 14 tweets
9 Apr
The US vaccination campaign is facing a fundamental challenge: getting the vaccine where it’s needed most. Millions of Americans are still unprotected, many of them at high risk of severe illness. Our 4th surge is beginning. Lives are at stake. 1 of thread/
1 in 3 people in the US have gotten at least one dose of vaccine—but that means 2 in 3 haven’t. Millions of people age 50-64 and 65+ who haven’t yet been vaccinated can still get Covid and are at much higher risk of severe illness or death, especially with the new variants. 2/
Some states are doing much better than others reaching older people: NH, VT, ME, RI, CT, MA, SD have given >1 dose to more than 85% of residents 65+ years old. In TN, WV, MS, Alabama, HI, and PR that proportion is less than 70%. 3/
Read 18 tweets
2 Apr
Covid Epi Weekly: The Centrality of Equity

Lots of good news on vaccines, but the virus and variants are gaining ground. Variants are spreading rapidly in the US, driving (along with premature opening) the fourth surge that’s now underway. 1/
I had planned to stop Friday night threads, but couldn’t help sharing thoughts on this week’s developments—there have been so many.

Fourth surge is building. Cases up 8%, test positivity up to 5.1%. Michigan situation worse, other states could follow. bit.ly/3duo8GL 2/
News on vaccines just keeps getting better. CDC study of mRNA vaccines found that Pfizer and Moderna vaccines blocked 90% of infections. Vaccinated people won’t spread much disease. HUGE implications for guidance for fully vaccinated people and the trajectory of the pandemic. 3/
Read 22 tweets

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