Oxidative stress, or an imbalance between free radicals and endogenous (self-made) antioxidants, increases in aging.
It leads to constant, low-level insulin receptor activation and failure to activate autophagy.
onlinelibrary.wiley.com/doi/full/10.11…
It leads to constant, low-level insulin receptor activation and failure to activate autophagy.
onlinelibrary.wiley.com/doi/full/10.11…
Fortunately, there's a way to fix this: exercise.
One of the most important ways in which exercise improves health is by increasing endogenous antioxidant production.
Exercise is a stress which the body recognizes by increasing its stress defenses.
sciencedirect.com/science/articl…
One of the most important ways in which exercise improves health is by increasing endogenous antioxidant production.
Exercise is a stress which the body recognizes by increasing its stress defenses.
sciencedirect.com/science/articl…
Older people have an attenuated antioxidant response to an acute bout of exercise, compared to young people.
But regular training can overcome this. sciencedirect.com/science/articl…
But regular training can overcome this. sciencedirect.com/science/articl…
Higher intensity exercise also activates endogenous antioxidant production more than steady-state exercise.
The endogenous antioxidants include glutathione, and the enzymes catalase and superoxide dismutase, as well as phase 2 detoxification enzymes.
tandfonline.com/doi/abs/10.108…
The endogenous antioxidants include glutathione, and the enzymes catalase and superoxide dismutase, as well as phase 2 detoxification enzymes.
tandfonline.com/doi/abs/10.108…
Increasing endogenous antioxidants is one of the most important ways that exercise fights aging.
Both higher intensity exercise, as well as regular exercise training are important in doing this.
Both higher intensity exercise, as well as regular exercise training are important in doing this.
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