This is a balanced assessment of the debate around the #OriginsOfCovid by @stephenburanyi in @guardian

I particularly like the honesty at the end of the piece.
theguardian.com/commentisfree/…
Rather than guessing which origin scenario is more likely, it’s good to acknowledge which scenario you would prefer to be true.

“A lab-leak would tarnish the job of scientific research for a lifetime and prove some of the worst people in the culture war – partially – right.”
My guess is, for most scientists, we would prefer if this virus has 100% natural origins - zero involvement of researchers or research activities.

Then, presumably, we wouldn’t have any blame for not putting in better biosafety / research regulations years ago or even today.
What about the general public? What would be the preferred scenario?

I suspect it would also be a natural origin because the ramifications of this pandemic starting in a lab are possibly too catastrophic for us to handle in the middle of said pandemic.
Some troubling questions would have to be asked, for example:

Do scientists know what they’re doing? Why did they downplay the risks? Is this work still ongoing in different countries?

How does this affect geopolitics w nations ramping up pathogen collection and manipulation?
It feels like it’s easier to fall back on the “China being China” hypothesis.

Specifically, the simple recipe of:
China > exotic animal trade > SARS pandemic

But this risks overlooking new recipes for disaster in 21st century:
Any country > pandemic pathogen research > pandemic
Btw lab-based pandemics do not require any conspiracy. They can be covered up just like natural pandemics. The first SARS outbreak was also covered up in China, and that one was 100% natural.
Some people claim that a giant conspiracy is needed for a lab leak to have happened & be covered up.

Wouldn’t the same apply to covering up the source of a natural outbreak?

How many would know the source with certainty? Having suspicions doesn’t mean you’re in on a conspiracy.
So who are the people who would prefer a lab leak #OriginsOfCovid to be true?

Maybe some of the experts who have been warning for years or since the start of the pandemic about the risks of some types of pathogen research.

It would feel vindicating. That you had foresight.
Personal victories aside, the main incentive is that if a lab origin is found, the scientific community can finally have a serious, motivated discussion about making pathogen research safer.

Even today, some scientists still dismiss the likelihood of a future lab-based outbreak.
The tone has changed over the past year from “we condemn all conspiracy theories of non-natural origins” to “a lab leak is possible but very unlikely.”

The next step might be “ok, lab-based outbreaks are likely & we actually need to do something to prevent these in the future.”
But there are also honestly bad people who want a lab leak to be true for mainly political reasons.

Scientists weighing in on the lab leak have been & continue to be slapped with the “you’re fuelling racists and right-wing people” charge.

wired.com/story/covid-19…
This point in @jetjocko’s @WIRED piece stuck out to me:

“Some of the people talking about a lab leak don’t want an answer. They want to amplify and in some cases even create, for mostly venal reasons, doubt.”

And, unfortunately, I think this is true for some people.
Like Adam Rogers points out, the #OriginsOfCovid is perhaps a perfect topic for weaponizing or commercializing uncertainty.

It is high impact enough, sensational enough to draw attention away from other political failures. At least for a short while.
However, I don’t like @jetjocko’s piece because it just adds to the polarization of this issue.

I know we’re not done mud slinging yet but I’m waiting for science writers to write about the people who genuinely want to find the #OriginsOfCovid
And this group of people who are truly motivated to find the #OriginsOfCovid span the political spectrum. No political group “owns” the lab leak hypothesis.

This group includes scientists who think a lab leak is unlikely, and also scientists who think a lab leak is likely.
I would like to see some articles focused on what unites us. Ask scientists what they think needs to be investigated next and if they will publicly call for an international investigation to be set up - looking into both natural and laboratory-based #OriginsOfCovid hypotheses.

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More from @Ayjchan

30 May
Today, karma finally kicked in. After spending the last year "just asking questions" and trying to fish out information relevant to the #OriginsOfCovid, I finally became a target of a conspiracy theory and an anonymous twitter mob.
I had been warned about this situation by well-intentioned colleagues, journalists, and even other anonymous twitter users. That a day would come when I would get attacked by anonymous users.

There was always a stream of online harassment, but it definitely peaked this week.
It definitely made me feel more empathy for other scientists who are in a similar situation. I had already been expressing empathy for them and actively asked people on twitter please not to attack because it just makes the conversation immediately adversarial and non-productive.
Read 4 tweets
30 May
I see this is raising eyebrows so I better nip it in the bud.

The work I did on human artificial chromosomes (HAC) had been widely presented at local meetings & on the lab website. I talked so openly about it that it could not be patented because it had been publicly disclosed.
The rest of the thread above rightly criticizes the meeting being “secret” - but I always thought that it had been labeled “secret” by the organizers to drum up media coverage (sorry, organizers!).

As far as I could tell, all of the research at that meeting was in public domain.
I’m sorry to reveal this gimmick but actually I think many of the scientists and organizers were eagerly awaiting journalists to call them to talk about the “secret” meeting.

In reality, most scientific meetings happen without any journalists paying attention.
Read 12 tweets
29 May
One thing I hate about the ongoing lab leak debate is how it is getting polarized as scientists against anti-science people.

You can hold a very pro-science (maybe even pro-virus engineering) POV, recognizing the value of virus research, while asking for safeguards.
I told @onthemedia @WNYC that I think pathogen research has a lot of value and we should not stop doing it.

There are surely creative ways scientists can develop vaccines and therapeutics without the risks of an uncontrollable lab-based outbreak.
The US is not going back into the 1900s while other countries race forward, send rockets to Mars & extend their population’s healthspan by decades.

We have to be leaders in scientific technology and also leaders in biosecurity. Both go hand in hand.

Coming from a 🇨🇦 in the US.
Read 6 tweets
28 May
Very happy to chat with @gbrumfiel on @NPR @NPRGoatsandSoda on the topic of the #OriginsOfCovid

Also glad to hear Dr Lipkin state that it’s possible this virus passed through a lab and accidentally leaked.

We need to launch a true investigation ASAP.

npr.org/sections/goats…
"Our lives depend on finding out how this virus got started so we can prevent another one from getting started 5 to 10 years from now."

Some might think I’m being dramatic but I don’t want to experience another outbreak like this, especially when I’m old.
npr.org/sections/goats…
The reason why I find it hard to make up a % likelihood for #OriginsOfCovid is because evidence can emerge & flip everything we know.

Eg what if tomorrow a whistleblower tells us they’ve been putting furin cleavage sites in natural SARS CoVs?

We are going to see U-turns.
Read 11 tweets
28 May
My twitter became an open forum for the #OriginsOfCovid

Starting out strong on the topics of gain-of-function research, SARS2-related viruses under study at the Wuhan Institute of Virology, and the lack of intermediate hosts for SARS2.

H/t @TheSeeker268 @franciscodeasis
Interesting comparison of CRISPR babies and virus research in China by @antonioregalado on @WBUR @radioopensource

And what scientists privately said about the #OriginsOfCovid
Read 9 tweets
27 May
I would like to suggest one thing to journalists asking about the #OriginsOfCovid - whether natural or lab-based.

Everyone is asking what do we know, what evidence do we have.

Ask scientists what we don’t know, what evidence are we still waiting for.
New evidence, new information should change a scientist’s perspective.

By forcing scientists to give you a likelihood estimate now, in the absence of definitive evidence, you’re constraining their future ability to change their minds.

We’ve already seen some minds changed.
Scientists should be able to change their minds completely in the span of a year.

The lab leak hypothesis has transitioned from a conspiracy theory to a near certainty in the minds of some scientists over the past year.
Read 4 tweets

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