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Lorrie Goldstein Profile picture
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1 Jun, 4 tweets, 2 min read
Canada is about to OK mixing AstraZeneca vaccines for the first dose with Pfizer and Moderna for the 2nd dose. The researcher who presided over the development of AZ says that's dangerous. #cdnpoli
"Our experience to date is that it produces pretty severe reactogenicity, so severe that we don't think that's going to be viable and by that I mean, you get your second dose if you flip it over, you'll get really sick, so I would not advise that” Sir John Bell said.
Source:
AstraZeneca-Oxford developer blasts Canada's approach to vaccine, says 'messing around is going to cost lives' ctvnews.ca/health/coronav… #cdnpoli
'Bell, who has intimate knowledge of the study currently taking place at the University of Oxford, said initial findings show severe side effect outcomes.'

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More from @sunlorrie

Lorrie Goldstein Profile picture
30 May
True: CDC gives much more info than our gov't. For Canada, I use a better site run by students at University of Saskatchewan.
Re CDC:
% of U.S. pop'n 12+ vaccinated:
59.6% at least 1 dose, 48% fully vaccinated
% of U.S. pop'n 18+ vaccinated
62.4% at least 1 dose, 51.2% fully
% of population 65+ vaccinated
85.8% at least 1 dose, 74.6% fully vaccinated
Data also explain why the US is so far ahead of us in opening up, while having lower rate of new infections. Combination of a far higher rate of people fully vaccinated, particularly most vulnerable groups, for a much longer period of time than Canada.
Read 5 tweets
Lorrie Goldstein Profile picture
30 May
Yep. B.C. health ministry takes same position:
"The provincial Ministry of Health said in a statement Thursday that when expired vaccines are administered 'in general, those who receive an expired vaccine should be advised, and recommended revaccination'."
It also says the expired products should then be sequestered in the refrigerator and returned to public health for safe disposal."
"A video meant for training purposes on the B.C. Centre for Disease Control's website says "expired vaccine is wasted." Other BCCDC and Health Canada documentation on the AstraZeneca vaccine indicate that it should be used before the expiration date ..."
Read 4 tweets
Lorrie Goldstein Profile picture
29 May
Ahem, Ontario: B.C. gov't on giving expired AstraZeneca vaccines to people:
The provincial Ministry of Health said in a statement that when expired vaccines are administered "in general, those who receive an expired vaccine should be advised, and recommended revaccination."
It also says the expired products should then be sequestered in the refrigerator and returned to public health for safe disposal.
'A video meant for training purposes on the B.C. Centre for Disease Control's website says "expired vaccine is wasted." Other BCCDC & Health Canada documentation on the AstraZeneca vaccine indicate that it should be used before the expiration date.'
Read 4 tweets
Lorrie Goldstein Profile picture
29 May
😂😂😂 "If you are wrong" ... blah, blah, blah ...
Health Canada extends expiry dates for AstraZeneca COVID-19 vaccines set to expire Monday toronto.citynews.ca/2021/05/29/hea…
'The Ontario government said Saturday certain lots of the Oxford-AstraZeneca COVID-19 vaccine that were set to expire on May 31 can now be used past their original expiry date following authorization by Health Canada.'
'Health Canada has issued an authorization to extend the expiry date of specific lots of the AstraZeneca COVID-19 vaccine from six months to seven months, following the review of submitted stability data,' said Alexandra Hilkene, press secretary to the minister of health.
Read 4 tweets
Lorrie Goldstein Profile picture
29 May
World Health Organization re expiry dates on AstraZeneca:
'Any vaccine that has passed its expiry date, including Covishield, should not be administered.'
'While discarding vaccines is deeply regrettable in the context of any immunization programme, WHO recommends that these expired doses should be removed from the distribution chain and safely disposed.'
'The shelf-life of a vaccine is a reflection of how long the vaccine retains its potency and stability at a given storage temperature and therefore its effectiveness. The shelf-life is used to establish the expiry date of each batch of the vaccine product.'
Read 4 tweets
Lorrie Goldstein Profile picture
28 May
No, the NACI recommendation is 'up to 4 months' because of the vaccine shortage, not '4 months.' The manufacturer recommendation is up to 3 months. I was told by pharmacy to book my 2nd dose after one month - book it, not get it - which has now gone to hell because of AZ shortage
The reason so many of us are trying to book it now is because we know that it's going to be almost impossible to do by the time the next substantial shipment of AZ to Ontario next week is 250,000 doses. More than a million Ontarians had AZ as their first dose.
See the problem?
Finally, where there is adequate supply -- not in Ontario for AZ -- provinces are already making plans, as they should, to reduce the interval between the 1st and second dose: B.C. to detail shortening interval between first, second COVID-19 vaccine doses: citynews1130.com/2021/05/27/bc-…
Read 4 tweets

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