Decision to recommend against antibody test after vaccination is yet another poor decision.
If CDC/FDA willing to say that full vaccination = immunity, then there is no good reason to say antibody positivity after vaccination does not equal immunity
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fda.gov/medical-device…
If CDC/FDA willing to say that full vaccination = immunity, then there is no good reason to say antibody positivity after vaccination does not equal immunity
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fda.gov/medical-device…
So on the positive side, if just getting a vaccine implies immunity per, then a positive response after a vaccine that is detectable by antibodies should imply that the person was vaccinated - thus protected.
But...
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But...
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But..on negative side - if someone fails to seroconvert to positive on EUA authorized Ab tests after vaccination... this would be crucial knowledge for someone to have and to talk to their doctor about.
FDA should be encouraging Ab testing post vaccine - esp serial measures
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FDA should be encouraging Ab testing post vaccine - esp serial measures
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I understand that FDA is making a statement that these Ab tests should not be used to definitively assess immune protection.
But the decision to comment against Ab testing post vaccination will be a net negative to our understanding of immunity in the long run.
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But the decision to comment against Ab testing post vaccination will be a net negative to our understanding of immunity in the long run.
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This is the type of data that we need a lot of data for. By pressing against Ab testing post vaccination, FDA is making it more difficult, not less, to measure the immunological correlates of protection that are so crucial for public health.
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This is yet another reason why we desperately need a new pathway at FDA focused on considering public health separately from medical diagnostics.
We must move away from a medical centric response to a pandemic and towards a public health centric response.
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We must move away from a medical centric response to a pandemic and towards a public health centric response.
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For clarity: FDA’s thinking is that if ppl get an Ab test post-vax and it says positive, then they may take fewer precautions
(Good ‘ol paternalism from FDA again)
But it really doesn’t make sense in light of current CDC guidance.... essentially: If vax’d, no precautions needed
(Good ‘ol paternalism from FDA again)
But it really doesn’t make sense in light of current CDC guidance.... essentially: If vax’d, no precautions needed
So as far as I can tell, if getting an Ab test after being fully vax’d, the only potential behavior change likely to take place (relative to current guidance) is one of being MORE careful – when the Ab test is negative.
If Ab test is pos post-vax, would behave as if vax’d!
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If Ab test is pos post-vax, would behave as if vax’d!
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