Apart from falsifying the “Central Dogma of Molecular Biology,” does this have any implications for whether mRNA vaccines can alter genomic DNA?
advances.sciencemag.org/content/7/24/e…
advances.sciencemag.org/content/7/24/e…
I can see the argument that these only act from certain templates, but let’s not forget 1) we falsely believed this couldn’t be true & literally called it “the central dogma” for almost a century and 2) it’s commonly believed that some half of our genome was inserted by viruses.
Ok so Crick’s original stating of the dogma in 1957/58 applied the exclusion to protein—>nucleic acid but not to RNA—>DNA, whereas Watson’s 1965 formulation applied it to both, so Watson’s but not Crick’s version had been falsified by reverse transcription.
And there’s nothing new here falsifying anything about the dogma, but it adds that the falsification of the Watsonian version isn’t just limited to viral reverse transcriptase but to juman ones as well.
I believe this had been suggested before, but I think this is the first irrefutable demonstration of a specific human enzyme.
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