Thread by @rcpsych

Our third day of virtual Congress and we welcome Alan Young, Prof. Bruno Etain - @BrunoEtain, Dr Monica Aas - @Monica__Aas and Dr Mario F P Juruena - @MarioJuruena to speak on: Early Life Stress In Severe Affective Disorders: From Neuroscience To Treatment #RCPsychIC

Heavy medical burden in Bipolar disorder #RCPsychIC

Over 40 a significant rise in metabolic syndrome in Bipolar disorder #RCPsychIC #Bipolar

Potential determinants of medical burden in bipolar disorder

Early exposure to stress in early childhood can add to the medical burden in bipolar disorder

#RCPsychIC #bipolar

Trialled on around 3000 people that have type 1, type 2 and NOS bipolar

#RCPsychIC #Bipolar

Gender may have a part to play in childhood trauma and association to Metabolic syndrome #RCPsychIC #Metabolicsyndrome

There are very few studies with trauma and medical burden in bipolar disorder. One below shows a sample taken in London #RCPsychIC #Bipolar

Thank you to Bruno with the fascinating data on Bipolar and stress.

@BrunoEtain

#RCPsychIC

Welcoming Dr Monica Aas - @Monica__Aas to the stage #RCPsychIC #Childhoodtrauma

The environment also affects telomere length - unemployment, divorce, other effects diet, poor sleep and low physical activity lengthens the telomore length in women.

#RCPsychIC

A study was undertaken: NORMENT study in Oslo, telomere length and childhood trauma were looked at and the sample is shown below

#RCPsychIC #Telomerelength

Males had shorter telomere length than females

Lack of studies of multiple suicide attempts

#RCPsychIC #Telomere

Study limitations

M childhood trauma retrospectively and didn't use perspective measures

#RCPsychIC

Thank you Dr Monica Aas for your talk

@Monica__Aas #RCPsychIC

We welcome Dr Mario F P Juruena - @MarioJuruena to talk to us about Genetic, HPA axis and early life stress impact in affective disorders #RCPsychIC

Genetically vulnerable people there is an impact of repeated stress and how it may participate a mood disorder #RCPsychIC

Structures are different in comparing the two #RCPsychIC

Serum Cortisol levels od healthy controls #RCPsychIC

Results summary from the study

Dr Mario F P Juruena - @MarioJuruena

#RCPsychIC

Thank you to all our speakers from this session, very informative and interesting data and studies.

Alan Young, Prof. Bruno Etain - @BrunoEtain, Dr Monica Aas - @Monica__Aas and Dr Mario F P Juruena - @MarioJuruena

#RCPsychIC