Thread by @rcpsych

We are delighted to be joined by Sophia Frangou - @Frangougroup Argyris Stringaris - @argStringaris and Heather Whalley who will be discussing: Dimensional and Categorical Psychopathology in Youth: Cognitive and Brain

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Presenter Profiles:

Sophia Frangou - @Frangougroup
Argyris Stringaris - @argStringaris
Heather Whalley - @heatherwhalley2

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Taking this approach

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Two studies will be discussed - ABC study and Imagen both have significant overlap at least conceptually

Imagen study we had 2000 young people

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The results of this study the effect is more pronounced in different regions

Imagen study:

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ABCD Study

-Diffused profile of brain organisation and the environment
-Negative effect on adverse perinatal brain activity

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ABCD study

Psychological outcome – suicidality nearly 700 children had considered ending their life – looking at what exposures in the study associated with suicidality.

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Parting thoughts from Sophia Frangou - @Frangougroup

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Welcoming to talk now is Argyris Stringaris - @argStringaris

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Basic challenges to psychiatric research in depression

-Genes
-Environment
-Active gene-environment correlation
-Passive gene-environment correlation
-Gene-environment interactions

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Reward aberrations in humans

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Longitudinal findings and specificity for depression

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Depression definitions

There were 9197 depression types

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Defining reward

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Welcome Dr Heather C Whalley! who is speaking about the trajectory of brain structural development in young people at familial risk of mood disorder

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Important: all individuals were well at the beginning and over time some became unwell

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There are structural brain differences at baseline

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Thank you to our speakers today Sophia Frangou - @Frangougroup Argyris Stringaris - @argStringaris and Dr Heather Whalley.

We hope you found the talk informative and educational as much as we did!

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