Here is an announcement from a few days ago: Ivermectin to be investigated as a possible treatment for COVID-19 in Oxford’s PRINCIPLE trial. This large well conducted trial will shed light on this topic. ox.ac.uk/news/2021-06-2…
“With known antiviral properties, ivermectin has been shown to reduce SARS-CoV-2 replication in laboratory studies. Small pilot studies show that early administration with ivermectin can reduce viral load and the duration of symptoms in some patients with mild COVID-19.”
“Even though ivermectin is used routinely in some countries to treat COVID-19, there is little evidence from large-scale randomised controlled trials to demonstrate that it can speed up recovery from the illness or reduce hospital admission.”
This RCT from March 2021 (N=476) was unable to show benefit. The duration of symptoms was not significantly different for patients who received a 5-day course of ivermectin compared with placebo. jamanetwork.com/journals/jama/…
A recent narrative analysis concludes that current evidence is not strong enough to say that ivermectin is a useful therapy for COVID19. Existing studies “suffer from various combinations of small sample size, poor trial design, not enough data reported.” blogs.sciencemag.org/pipeline/archi…
• • •
Missing some Tweet in this thread? You can try to
force a refresh
