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Hwa Shi-Hsia

1 Jul, 3 tweets, 2 min read

If you had mild Covid DO NOT assume "I have a good immune system therefore I'm protected now". It could be you were just lucky to have a low infection in the 1st place & it was so low your body didn't even have a chance to form strong antibodies.
#SARSCoV2 #SARSCov2antibodies

Plain English explanation of above graph:
Seropositive = got antibody
Seronegative = no antibody
Ct is opposite of how much viral RNA, low Ct *roughly* means high virus, high Ct~low virus

Weimin Liu et al. "Predictors of Nonseroconversion after SARS-CoV-2 Infection "
wwwnc.cdc.gov/eid/article/27…

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Hwa Shi-Hsia

@coolvirus

29 Jun

Comparison of #SARSCoV2 cultures in well-differentiated, primary epithelial cells in air-liquid interface from 12 different mammals species. I'm guessing the 1 paragraph & table of Methods on the cell culture has like months of work behind it.
(fig1: left 33C, right 37C)

Since these types of cultures can be tricky and susceptible to poor cell quality they used influenza A (human isolate) and influenza D (bovine isolate) as positive controls for virus infection.

Except for 1 bat (both bats are American species), all the cultures were infectable by 1 or both #influenza viruses, showing the cells are fine, but only rhesus macaque and domestic cat AEC cells were infectable by #SARSCoV2.
Hope that spillback into American bats will not occur.

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