1/9. In England, #SARSCoV2 infection rates in school-aged kids & #COVID19 outbreaks have both ⬆️ in recent weeks (latest data 4 July) but that does not change the narrative on kids & their role in infection/transmission in school
2/9. No one has claimed that kids don’t get infected or don’t transmit #SARSCoV2 to others. But the data suggest that lower risk with kids than adults. Eg. We don’t see two-thirds of staff/students infected in a single outbreak as we do in care homes 👉 thelancet.com/journals/eclin…
3/9. We & others have shown that #SARSCoV2 cases & outbreaks reflect community infection rates. Cases in kids generally follow adults *unless* adults are in lockdown & kids continue to go to school. This happened in Nov/Dec 2020 & Mar/Apr 2021. See👇👇
4/9. After the Jan 2021 lockdown, schools opened on 08 March for 3 weeks (black circle). Cases were highest in secondary school children when mass LFD testing was implemented before they were allowed back in school, but then declined & remained low (they also wore masks in class)
5/9. After the Easter holidays, too, infection rates remained low in all school-aged children for *6 weeks* since mid-April (blue circle), when most of the adults were still in national lockdown & despite the emergence of the Delta variant in England - outbreaks too were limited
6/9. From 17 May (week 20), we eased into step 3 of opening lockdown & cases ⬆️ rapidly in all ages, esp 20-29 & 10-19 year-olds. Only 1 of these groups was in school.
7/9. Interestingly, infections by age are better seen in ONS Survey (community testing, random households). Infections in primary & secondary school-aged kids remained low & only started ⬆️ after cases started increasing in year 12 to age 24 (~mid-June) 👉ons.gov.uk/peoplepopulati…
8/9. School outbreaks have also increased, especially after 17 May (red circle), although important to remember there are ~24,000 schools & <300 outbreaks (1-2% of schools). Also, outbreaks are defined as 2+ cases but these cases don’t have to be linked or infected in school 👇
9/9. In conclusion, #SARSCoV2 cases/outbreaks in schools remained ⬇️ when adults were in lockdown. This changed when lockdown eased (17 May). Vaccines will help keep community infection ⬇️ but we need more evidence-based mitigations in schools not just 4 #SARSCoV2 but all viruses
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1/4 Childhood #COVID19 deaths. This preprint by @RCPCHtweets & @PHE_uk provides critical new information about #SARSCoV2 and kids which we didn’t have until now. Here’s why the small numbers in this paper matter 🧵
2/4 Death is the most objective outcome & can be accurately measured in countries like England. The results show ~3,000 of 12 million kids died in 1 year & only 61 with #SARSCoV2. Detailed medical record analysis showed only 25 (42%) died *of* #COVID19
3/4. Of the 25 kids who died of #COVID19, 19/25 (76%) had underlying conditions & of these 15/19 (60%) had a life-limiting condition & mostly with 2 or more medical conditions, esp. severe neurological conditions
2/5 Compared to 2 doses of the same vaccine brand, mixing Pfizer/AZ vaccines was associated with higher rates of severe reactions & requiring medical attention after the 2nd dose: esp. in younger adults, in women & in those with previous #COVID19 🧵
3/5 Adults who had a severe reaction after their 1st dose of #COVID19 were more likely to have a severe reaction after 2nd dose, whichever vaccine they received, but risk of severe reactions increased if 2 different vaccine (AZ/Pfizer) brands given 🧵
1/ News outlets & people on social media have been misinterpreting data on exposures prior to diagnosis as places where people caught #SARSCoV2 (provided in the @PHE_uk Weekly Reports)
2/. UK has been in lockdown since Nov. In Mar 2021, only schools reopened ➡️ 9 million children & education staff were out in the community. The figure below shows that a person was attending school prior to testing +ve for #SARSCoV2 - not that they caught #SARSCoV2 in school
3/ But as we eased into step 3 of opening lockdown, people were more likely to have visited other venues prior to testing +ve for #SARSCoV2
Here’s the same graph for the latest week reported. Eating out & “other” are now more frequent because restaurants & shops are open 👇