This is not unexpected. If the authors of the retracted ivermectin study claim that the data was not really the data for their paper, they now need to explain:
1. Why did they upload fake data that quite clearly matched their results?
3. The implausible/impossible values remaining in the text
4. The incorrect and bizarre statistical tests
5. Why it is only NOW that we're told the data us fake. Was it a joke? A prank???
5. (cont.) Seriously, how do the authors explain the fact that they uploaded a dataset, said it was the data of their study, and now claim it wasn't? How do we reconcile that with what they claim now?
6. It is also worth noting that this is not actually a public statement by the authors, but rather a tweet supposedly on their behalf by someone else. I await them actually speaking because it's possible this isn't actually Professor Elgazzar
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So, @Covid19Critical does not agree with me, and says that the conclusions of meta-analyses do not change at all once excluding the retracted ivermectin study
Let's go over exactly why I said that removing the study makes a huge difference 1/n
2/n I went over this in my article, which you can find here, but I'll repeat the precise analysis I've done on twitter, because I think it's a fair question
To be clear - I'm not perfect, and not everything I say is right!
3/n Judge for yourself whether it is fair to argue that removing Elgazzar largely eliminates the benefit for mortality here, the headline finding and the primary analysis of the paper
So, one of the biggest studies to date on ivermectin for COVID-19 has issues significant enough that, if not fraud, are so serious that it invalidates the study without further explanation
2/n Firstly, none of this would've been possible without @JackMLawrence, who uncovered this in the first place and investigated it himself well before any of us gronks got on board
3/n The basic story is pretty astonishing. I've previously written about this study, Elgazzar et al, and why there are some indications that it's low-quality and potentially very unreliable
Another day, another systematic review and meta-analysis of the same ivermectin research published
This one is positive. I don't think it should be 1/n
2/n Study is here, and generally it looks fine - search strategy was decent, they followed most guidelines (I.e. PRISMA), and overall the methodology was pretty reasonable for the stated purpose academic.oup.com/ofid/advance-a…
3/n In fact, it is amazingly similar to the other systematic review that I looked at recently, down to THE SAME DETAILS THAT ARE WEIRD
This paper was recently published, arguing that vaccines cause as much death as they prevent and so we should stop vaccinating people
I rarely say this, but it is truly awful and should be retracted as soon as possible 1/n
2/n The paper is here. It is truly woeful, but worth reading just to see how easy it can be to make a plausible-sounding argument if you are very free with your methodology mdpi.com/2076-393X/9/7/…
3/n The authors did two things - they calculated a Number Needed To Vaccinate (NNTV) from a propensity-matched cohort study done in Israel. They also calculated the number of deaths reported through the Dutch vaccine reporting system
HOW TO REDUCE YOUR COFFEE INTAKE FOR A BETTER LIFE
STEP 1: NO
☕️☕️☕️☕️☕️
If anyone's wondering, while there are few/no health benefits directly attributable to drinking coffee, there is also consistent evidence that even quite high intakes are unlikely to be harmful to your health
(Obviously this is not a blanket endorsement, if your doctor tells you to drink less coffee you probably should. If your naturopath tells you to drink less coffee, on the other hand, you should stop seeing a naturopath)