From @sciencecohen @ScienceMagazine on @WHO next steps #originsofcovid
“Koopmans.. would welcome broadening the existing group’s expertise.. to conduct lab audits and to study the blood of more humans who.. may have been exposed.. before the outbreak”
sciencemag.org/news/2021/07/w…
Gerard Keusch, who signed both infamous Lancet letters and partnered with Peter Daszak to apply for a grant, said of the new SAGO: “allowing individuals and governments to nominate themselves.. will result in a partisan, selective process and not lead to the best composition.”
I would like to ask Keusch if he witnessed the China-WHO joint study phase I team member selection process and whether he considers it non-partisan and of the “best composition”.
And in particular whether he believes members with reasonably perceived conflicts of interests were able to act in an entirely “private capacity” while in the study group:
Remember this absurdity where one of the international experts, Peter Daszak vouched for the WIV lab, his long time collaborator, and didn’t ask to see their extensive pathogen database which he partially funded and is a part of?
I think an open nomination process is going to be just fine. Things can only improve from where we currently stand.
Just think about how much valuable time in Phase I of their joint study was devoted to investigating whether the virus might’ve originated from frozen foods #PopsicleOrigins
I also think the @WHO team and SAGO could initially focus the investigation on venues that do not require China’s cooperation. A gem of a study was only revealed this June, 1.5 years post-outbreak. Contradicting the China-WHO report that no live wild mammals were sold in Wuhan.
There could be more of these studies just languishing behind the curtain of peer review. Let’s start with the journals outside of China first to build a comprehensive set of knowledge about info and data concerning early cases, SARSrCoVs, and subjects related to #OriginsOfCovid
On the market, even the Chinese CDC director realized in May 2020 it was just a later cluster of cases.

“At first, we assumed the seafood market might have the virus, but now the market is more like a victim. The novel coronavirus had existed long before”
newsweek.com/wuhan-seafood-…
The China-WHO team understood as much. Regarding the Dec 2019 early cases, including those from the market, “those data became less important to team members.. because they realized that the pandemic predated those cases.”

Possibly as early as Sep 2019.
wsj.com/articles/covid…
Finding viral RNA on surfaces where a superspreader event occurred is 100% expected and does not necessarily point to natural spillover.

Take for example the first cruises to be hit with Covid-19. They weren’t shipping bats, pangolins, or raccoon dogs.

cdc.gov/mmwr/volumes/6…
“SARS-CoV-2 RNA was identified on a variety of surfaces in cabins of both symptomatic and asymptomatic infected passengers up to 17 days after cabins were vacated on the Diamond Princess but before disinfection procedures had been conducted.”
But now we are being treated to a multi-market hypothesis - proposed by top virologists - that the SARS2 virus not only jumped from an animal to a human being once, but multiple times at multiple locations in Wuhan.

Evidence?
In my view, the multi-market hypothesis is more speculative and less plausible, relying on more unsubstantiated assumptions and with less circumstantial evidence, than the genetically engineered #OriginsOfCovid hypothesis.
Please remember that the market that the first case was associated with was not anything like a live animal market.
Possibly on the level of the “SARS2 came from space” hypothesis, which got past peer review.

People, this is a peer reviewed scientific article published in Advances in Genetics.

ncbi.nlm.nih.gov/pmc/articles/P…
IMO lab escape or genetic engineering hypotheses are more plausible than multi-market.

“You can't distinguish between the two origins from just looking at the sequence.. you want to know were there people.. who were manipulating viral genetic sequences?”

caltech.edu/about/news/the…
Wrapping up, we need parallel investigations.

We should expect best efforts from the WHO to return to transparent and timely science-focused work on #OriginsOfCovid but we can’t rely on just the WHO to investigate.

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More from @Ayjchan

20 Jul
New information or clarifications relevant to the #OriginsOfCovid continue to come to light on a regular basis.

In the short time between when I spoke with @NPR @FoodieScience and today, @washingtonpost published their discovery that China @WHO report suffered editing errors…
Unfortunately one of the known errors impacts the map of early covid cases in Dec 2019- this data is inconsistent with what was reported in Wuhan and yet underlies the first figure of the critical review by Holmes et al.
This is very problematic because a map with errors is influencing the judgment of scientists who have no access to primary data.
Read 10 tweets
19 Jul
Getting a bit weary of debunking articles trying to debunk information surrounding the lab leak hypothesis.

This @snopes article does a good job debunking some straw men but I think makes some critical errors.
snopes.com/news/2021/07/1…
In my opinion, it starts off on the wrong foot.

Some powerful scientists indeed unfairly rejected the notion that SARS2 came from a lab as a conspiracy theory. And internet sleuths did uncover damning info pointing to a possible lab origin of SARS2. usrtk.org/biohazards-blo…
This is not a good look for scientists and I reject that scientists as a whole are judged based on these Lancet letters.
Read 28 tweets
18 Jul
A very insightful piece on vaccine hesitancy:
"most vaccine skepticism, if by that we mean reluctance, is not based on conspiracy theorizing — it’s based on risk-benefit calculations"
nationalreview.com/2021/07/convin…
"People find acts of God easier to accept than mistakes of their own volition. So they may find it easier to accept the risks of facing COVID in nature, which they did not choose to get, than the unknown risks of a vaccine that they did consciously choose to take."
I think one major public health/sci comm mistake was emphasizing sterilizing immunity: vaccination = Never getting infected and Never transmitting virus to others.

When the point of being vaccinated = not developing severe covid, reaching herd immunity.
globalnews.ca/news/8003930/i…
Read 5 tweets
18 Jul
Frustrating to read in July 2021 when vaccines have proven effective and are readily available in the US.

“Nurses are watching families navigate end-of-life decisions for young people who have no advance directives or other legal documents in place.”

theatlantic.com/health/archive…
I know some well educated people who insist on staying unvaccinated. Due to how they were raised or where they grew up, they would rather take their chances with covid-19 (the delta and other new variants) than take a vaccine that has been administered to 100s millions of people.
The problem is that healthcare workers and the vulnerable people in society are now “putting themselves in harm’s way for people who’ve chosen not to protect themselves”

“Some health-care workers are starting to resent their patients—an emotion that feels taboo.”
Read 6 tweets
17 Jul
Looking forward to more details on how the “dream team” helped Kristian Andersen shift from 60-70% sure Covid-19 came from a lab to “we do not believe that any type of laboratory-based scenario is plausible” and “rules out laboratory manipulation”. thetimes.co.uk/article/sage-a…
Read 11 tweets
17 Jul
In this @Medium post, I counter the claim that there is a substantial body of evidence pointing to a natural origin of COVID-19.

All publicly available evidence and information are consistent with both natural and laboratory origin scenarios.
ayjchan.medium.com/a-response-to-…
Only with more data and information can scientists confidently evaluate the likelihood of each origin hypothesis.

A credible, transparent, evidence-based, and international investigation of the origin of Covid-19 is not only vital but also feasible.
Key points:
1. The 2003 epidemic SARS-CoV was quickly traced to proximal animal sources of the virus. Yet, despite greatly improved surveillance technologies and capabilities, an intermediate host for SARS-CoV-2 has still not been found more than 1.5 years.
Read 24 tweets

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