New information or clarifications relevant to the #OriginsOfCovid continue to come to light on a regular basis.

In the short time between when I spoke with @NPR @FoodieScience and today, @washingtonpost published their discovery that China @who report suffered editing errors…
Unfortunately one of the known errors impacts the map of early covid cases in Dec 2019- this data is inconsistent with what was reported in Wuhan and yet underlies the first figure of the critical review by Holmes et al.
This is very problematic because a map with errors is influencing the judgment of scientists who have no access to primary data.
So @FoodieScience is absolutely right on this point: “all the data presented to support Worobey's hypothesis comes with caveats — big caveats.”
And Mike Worobey is also on point:
“But if new data comes to light tomorrow, his thinking may shift again, Worobey says. That, in many ways, is the way science works.”

npr.org/sections/goats…
We will need to wait and see how @WHO respond to @washingtonpost @evadou @emilyrauhala on why the first reported covid case was mapped on the wrong side of the river when it was actually in the district where WIV is located…

washingtonpost.com/world/asia_pac…
Spokesperson @who didn’t seem to think this error was consequential:
“WHO spokesman, said.. the question of where the first-known patient lived relative to the river was not relevant to competing hypotheses about the origin of the virus. The issue is not important, he wrote…
… because “the current first known patient is most probably not the first case.””

@who this doesn’t absolve your joint report with China of having to present accurate data and information.
The maps in the report annex are not only super low resolution but now also appear to have major error in how the data was plotted.
More on the point made by WHO that the earliest cases (Dec 2019) in their map are probably not the first cases- the data their team had seen could possible indicate covid cases as far back as September 2019.
Instead of relying on a low resolution map that we know is inconsistent with early case reports, we really need to be asking for more data or at the very least interviewing people outside of China with privileged information from late 2019, early 2020.
We know that the way early covid cases were identified suffered from ascertainment bias. At the time, authorities thought the market was the source of the virus so they targeted people who visited the market and kept finding more market-linked cases instead of looking elsewhere…
The China-WHO team reported the case criteria in their annex, which underlies the map of early cases in their report that underlies the figure in Holmes et al.

Exposure to the market was a key factor in determining whether a patient was a suspected case.
ayjchan.medium.com/a-response-to-…
In summary,
1. We do not have access to the primary data
2. We know early cases were identified in a biased way
3. These were mapped inconsistently with reported case info
4. Earliest case should have been on side of river where WIV is located instead of where market is located.
5. There were likely covid cases as early as September 2019 that we don’t have information about.
6. Previous examples of natural spillover and lab escapes tell us that home address is not a particularly useful metric for tracking origin of an outbreak.

ayjchan.medium.com/a-response-to-…

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More from @Ayjchan

19 Jul
Getting a bit weary of debunking articles trying to debunk information surrounding the lab leak hypothesis.

This @snopes article does a good job debunking some straw men but I think makes some critical errors.
snopes.com/news/2021/07/1…
In my opinion, it starts off on the wrong foot.

Some powerful scientists indeed unfairly rejected the notion that SARS2 came from a lab as a conspiracy theory. And internet sleuths did uncover damning info pointing to a possible lab origin of SARS2. usrtk.org/biohazards-blo…
This is not a good look for scientists and I reject that scientists as a whole are judged based on these Lancet letters.
Read 28 tweets
18 Jul
A very insightful piece on vaccine hesitancy:
"most vaccine skepticism, if by that we mean reluctance, is not based on conspiracy theorizing — it’s based on risk-benefit calculations"
nationalreview.com/2021/07/convin…
"People find acts of God easier to accept than mistakes of their own volition. So they may find it easier to accept the risks of facing COVID in nature, which they did not choose to get, than the unknown risks of a vaccine that they did consciously choose to take."
I think one major public health/sci comm mistake was emphasizing sterilizing immunity: vaccination = Never getting infected and Never transmitting virus to others.

When the point of being vaccinated = not developing severe covid, reaching herd immunity.
globalnews.ca/news/8003930/i…
Read 5 tweets
18 Jul
Frustrating to read in July 2021 when vaccines have proven effective and are readily available in the US.

“Nurses are watching families navigate end-of-life decisions for young people who have no advance directives or other legal documents in place.”

theatlantic.com/health/archive…
I know some well educated people who insist on staying unvaccinated. Due to how they were raised or where they grew up, they would rather take their chances with covid-19 (the delta and other new variants) than take a vaccine that has been administered to 100s millions of people.
The problem is that healthcare workers and the vulnerable people in society are now “putting themselves in harm’s way for people who’ve chosen not to protect themselves”

“Some health-care workers are starting to resent their patients—an emotion that feels taboo.”
Read 6 tweets
17 Jul
From @sciencecohen @ScienceMagazine on @WHO next steps #originsofcovid
“Koopmans.. would welcome broadening the existing group’s expertise.. to conduct lab audits and to study the blood of more humans who.. may have been exposed.. before the outbreak”
sciencemag.org/news/2021/07/w…
Gerard Keusch, who signed both infamous Lancet letters and partnered with Peter Daszak to apply for a grant, said of the new SAGO: “allowing individuals and governments to nominate themselves.. will result in a partisan, selective process and not lead to the best composition.”
I would like to ask Keusch if he witnessed the China-WHO joint study phase I team member selection process and whether he considers it non-partisan and of the “best composition”.
Read 20 tweets
17 Jul
Looking forward to more details on how the “dream team” helped Kristian Andersen shift from 60-70% sure Covid-19 came from a lab to “we do not believe that any type of laboratory-based scenario is plausible” and “rules out laboratory manipulation”. thetimes.co.uk/article/sage-a…
Read 11 tweets
17 Jul
In this @Medium post, I counter the claim that there is a substantial body of evidence pointing to a natural origin of COVID-19.

All publicly available evidence and information are consistent with both natural and laboratory origin scenarios.
ayjchan.medium.com/a-response-to-…
Only with more data and information can scientists confidently evaluate the likelihood of each origin hypothesis.

A credible, transparent, evidence-based, and international investigation of the origin of Covid-19 is not only vital but also feasible.
Key points:
1. The 2003 epidemic SARS-CoV was quickly traced to proximal animal sources of the virus. Yet, despite greatly improved surveillance technologies and capabilities, an intermediate host for SARS-CoV-2 has still not been found more than 1.5 years.
Read 24 tweets

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