In this small study of 39 breakthrough cases, 7 of 36 (19%) followed for 6 weeks got long COVID.

⚠️This may be an overestimate as asymptomatic breakthrough infections were likely missed in the full sample of 11,453 people.

However, it shows vaccinated people can get long COVID.
It’s also important to remember that these people first had to get infected and become a breakthrough case before they were at risk of developing long COVID.

Developing long COVID after vaccination is probably uncommon (but not rare).
The risk of becoming infected after vaccination should decrease as more of the population is vaccinated. Even if herd immunity isn’t reached, there should be some herd protection.

But until transmission is brought to low levels, it would be a good idea to keep wearing a mask. 😷
Note: There were 11,453 vaccinated (with the Pfizer-BNT vaccine) healthcare workers in this study, of whom 1,497 were tested during the study period.

The study ran from January to April 2021 in Israel (when the alpha variant was dominant). The third wave there peaked in January.

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Dr Zoë Hyde

Dr Zoë Hyde Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @DrZoeHyde

28 Jul
You’ve probably seen reports suggesting effectiveness of the Pfizer-BNT vaccine has dropped markedly in Israel in recent weeks, possibly because of waning immunity.

That claim may be wrong.

I think effectiveness has been underestimated, and this thread appears to confirm it.
The issue is that vaccination levels aren’t uniform in Israel. There are areas with very high coverage, and pockets where coverage is much lower.

A problem then arises if the country-wide average is used.
Israel’s fourth wave, driven by the delta variant, is only just starting to reach the people in the less vaccinated areas.

So until now, it was mostly vaccinated people who were getting exposed.
Read 5 tweets
25 Jul
You know what worries me a lot more than COVID-19? People. Particularly angry, fearful people.

Make no mistake; they are afraid. Denial of reality is a coping mechanism for many. But you can’t avoid reality forever, and eventually they’ll turn on the enablers of that delusion.
The current crop of politicians who’ve promised freedom won’t be able to deliver it.

We’ll inevitably have to live with some level of restrictions until we have more of the world vaccinated with better vaccines. Will these people accept that?
But there’s a bigger problem. Many countries could have eliminated COVID-19 in early 2020 had they chosen to. It would not be a stretch to say that it was to an ideological choice to have a pandemic, to some degree.
Read 7 tweets
18 Jul
Two new pre-print studies from Israel suggest the Pfizer-BNT vaccine is 80% effective against infection & 88% effective against transmission to household contacts. This is very good, but a significant proportion of vaccinated people can still get infected.
medrxiv.org/content/10.110…
Researchers looked at the household contacts of confirmed COVID-19 cases.

7.5% of vaccinated household contacts became infected compared to 37.5% of unvaccinated contacts.
medrxiv.org/content/10.110…
These studies were conducted at a time when the alpha variant was dominant.

It’s likely that effectiveness of the Pfizer-BNT vaccine against transmission is slightly lower for the delta variant.
Read 5 tweets
13 Jul
My latest piece for @ConversationEDU:

No, we can’t treat COVID-19 like the flu. We have to consider the lasting health problems it causes. #COVID19
theconversation.com/no-we-cant-tre…
No, we can’t treat COVID-19 like the flu. We have to consider the lasting health problems it causes.

Translations:

🇩🇪Deutsch: translate.google.com/translate?hl=d…

🇳🇱Nederlands:
translate.google.com/translate?hl=n…

🇫🇷Français : translate.google.com/translate?hl=f…
No, we can’t treat COVID-19 like the flu. We have to consider the lasting health problems it causes.

Translations:

🇯🇵日本語: translate.google.com/translate?hl=j…

🇵🇹🇧🇷Português: translate.google.com/translate?hl=p…

🇪🇸Español: translate.google.com/translate?hl=e…
Read 4 tweets
26 Jun
I’m not confident the Sydney delta variant outbreak will be contained. This fundamentally changes the risk/benefit ratio of the AstraZeneca vaccine for those over 60.

Even a single dose provides >70% protection against hospitalisation & is worth the 0.00002% risk of blood clots.
A person aged over 60 years has at least a 7% chance of being hospitalised if they become infected with the original strain of the virus.

This rises to at least 10% with the alpha variant (B.1.1.7).

The risk likely exceeds 20% with the delta variant.
bmj.com/content/373/bm…
The risk of death from COVID-19 also rises steeply with age.

The figure below shows the estimated proportion of people who die after becoming infected with the original strain of the virus.

Remember the delta variant is associated with additional risk.
link.springer.com/article/10.100…
Read 5 tweets
16 Jun
(1/4) Study showing the B.1.1.7 (alpha/UK) variant is associated with a 52% increase in the risk of being hospitalised compared to the original strain. The increased risk mainly affects those aged 30 years and older. The risk of death is increased by 59%.
bmj.com/content/373/bm…
(2/4) The authors also calculated the absolute risk of being hospitalised after testing positive with the B.1.1.7 (alpha/UK) variant.

For children (<10 years old), it was about 1%, and for adolescents, it was 0.7%.

This was not significantly different than the original strain.
(3/4) For 20-29 year olds, the absolute risk of being hospitalised was 1.9% (previously 1.5%).

For 30-39 year olds, the absolute risk of being hospitalised was 3.4% (previously 2.6%).
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

:(