I really like the idea of re-routing viral traffic, put forth by virologist Stephen Morse.
Natural routes of viral traffic continue to exist and be amplified. But new routes of viral traffic, related to research activity, have emerged in the modern era... noemamag.com/the-routes-of-…
One early example of a novel pathogen emerging due to research activity is Marburg virus, "first recognized in 1967, when outbreaks of hemorrhagic fever occurred simultaneously in laboratories in Marburg and Frankfurt, Germany and in Belgrade, Yugoslavia" cdc.gov/vhf/marburg/in…
And that was generations ago.
Today, we can go from a virus sample to a genome sequence in a few days, and from a genome sequence to a completely synthetic perfect (seamless) copy of that genome in a matter of weeks.
While there were respected scientists who thought “that H5N1 could never become airborne between mammals,” he said, “I wasn’t convinced. To prove these guys wrong, we needed to make a virus that is transmissible.”
Please, no one ever again tell a scientist that they cannot make a virus airborne among mammals or more capable of causing a pandemic.
They will try and show you it is actually possible. And succeed.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
Would be good to track the 2000+ individuals (all adults vaccinated) from this cruise who are disembarking in the Bahamas tomorrow and see how many test positive for Covid-19 over the next 2 weeks. usatoday.com/story/travel/c…
There are many things we don’t know *yet* about the delta variants and vaccines:
How much do our vaccines protect against infection, asymptomatic or symptomatic, by delta?
How much do infected vaxed individuals spread the virus compared to infected non-vaxed individuals?
We do know that several top vaccines continue to protect against severe covid-19. So it’s not particularly worrying when vaxed people get delta (although there are exceptions and some breakthrough cases suffer greatly). What’s worrying is the spread of delta to the unvaxed.
NIH explained to Senator Grassley how NIH-funded SARS/MERS-like chimeric CoV work at WIV had not been determined to meet USG criteria for GOFROC covered by federal funding pause or P3CO Framework.
“during the course of the grant, the grantee proposed to place a small portion of the newly identified bat coronaviruses into a larger portion of MERS-CoV to understand the potential origins of MERS-CoV in bats.. conducted at WIV”
Can this proposal pls be shared with the public?
Another question: Did NIH-funded WIV work turn out to be “instrumental to the unprecedented rapid development of vaccines, therapeutics, and diagnostics to address the COVID-19 pandemic”?
Important for this to be substantiated with data since similar work continues to be funded.
Internal CDC document cites "unpublished data from outbreak investigations and outside studies showing that vaccinated individuals infected with delta may be able to transmit the virus as easily as those who are unvaccinated." washingtonpost.com/health/2021/07…
"Even people who are vaccinated should wear masks indoors in communities with substantial viral spread or when in the presence of people who are particularly vulnerable to infection and illness, the CDC said."
"public trust in vaccines may be undermined when people experience or hear about breakthrough cases, especially after public health officials have described them as rare."
Plotting the lineage percentages of new sequences each day over the past 6 months. Visualized using covidcg.org@CovidCg
Red = Alpha variant
Dark blue (outlined) = Delta variant
@CovidCg Under the blue wave of Delta which was first detected in the USA in Feb 2021, there is a green sliver indicating the newer AY.3 sublineage of Delta.
This means that almost all of the most recent USA sequences on the GISAID database are Delta.