Arizona (ppn 7M) gives us a foretaste of where NSW (ppn 8M) will be in about a month but with a lower vaccination rate leading to a higher death rate (assume doubling time of 2 weeks, starting at a baseline of 650 cases/day) #DeltaTsunami
Articles like this that speak only of statistics really only tell part of the story. Even the blunted mortality from vaccination only cushions the blunt impact abc15.com/news/coronavir…
The everyday personal narratives that fill our lives will be more like this. People complain of the pain of lockdown and of its hardships. But when the tsunami of death hits us, the pain will be of a different order of magnitude
People will complain that it is hyperbolic and alarmist to claim that NSW could get from 600 cases/day to Arizona's 2900. By linear growth its hard to get there, but since COVID spreads by exponential growth, it's just two easy steps away: 650-1300-2600
Given that there will be a lag before seeing the impact of stepwise tightenings of lockdown, we have effectively reached the next step of 1300 in the next couple of weeks. The question is whether tighter lockdown can halt or slow the march to the next step of 2600
For those beholden to the political spin masters who deny that NSW is seeing unbridled exponential growth, here is the refutation. Change the graph from linear to log scale and the line becomes a straight line. We're in exponential growth. End of story
And no sooner as I had spoken...this. Once again, yes indeed, we are in unchecked exponential growth
Here are some predictions based on proper mathematical modelling. It confirms my crude estimates and we'll hit 1200 very soon. Next station on the delta express, 2400

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More from @ToshiAkima

1 Sep
The unspoken assumption of "living with COVID" is that it is in the economic best interests of the nation to allow the self-regulating forces of competition to liquidate the uncompetitive for the sake of net economic gain. Sacrificing lives to the gods reaps monetary rewards
This is a form of Social Darwinism in that it assumes that the self-regulating force shaping society for the better is that of the principle of capitalism as the "survival of the fittest". One devalues the "wealth of nations" by interfering to stop it
The assumption comes along that allowing the weak to perish under natural forces of competition increase the "wealth of nations". Economic intervention to support the economy during lockdowns keeps non-viable entities alive in violation of the law of the survival of the fittest
Read 13 tweets
31 Aug
Observations of a Tsunami. Last week I optimistically predicted that NSW would track more like Arizona but this week gives me cause to doubt that. We might be headed on a one-way trip to Florida instead
I predicted on the 21st that it would take 2 weeks to reach a daily case number of 1300. I was accused of scaremongering. We reached +1200 in about 8 days instead. This reflects NSW frontline staff's experience with a surge more vehement than anticipated
If we start on Monday 30/8/21 at 1200 cases/day with an exponential doubling time of 8 days then by next Tuesday we could be at 2400/day. In another 8 days, 4800/day. If the peak occurs in October there's plenty of time to squeeze in another exponential doubling to 9600/day
Read 11 tweets
31 Aug
Dear Journalists. Please take note and hold politicians accountable by challenging their falsehoods. This is basic high-school level maths, not rocket science. In this thread, I will explain it in easy-to-grasp terms
This is what "linear growth" looks like. It goes 2-4-6-8-10-12 etc. It takes quite a few steps to get from 2 to 12. That means growth over time often tends to be slower in a linear growth model. The graph looks like this. Linear = straight line Image
With exponential growth, you get serial doublings. So if you start at 2, you go 2-4-8-16-32-64. Exponential growth allows you to get from 2-12 in far fewer steps than with linear growth. The curve looks like this Image
Read 14 tweets
30 Aug
This needs to go viral in Australia. The story line being that it may not be possible to open up like the UK has done because we relied excessively on the Pfizer vaccine instead of AstraZeneca. The AU Pfizer based double-vaccination strategy now in flames
The reason for this might be because even though antibody levels falls with time for both Pfizer and AstraZeneca vaccines, the better T-cell mediated response from AZ might compensate for this thelancet.com/journals/lance…
The conclusion is that we cannot use the UK as a template for a vaccination strategy in Australia. We are forced to follow the Israeli model and forget whatever BoJo did or said. As the science changes, so the public policy must change with it
Read 4 tweets
14 Aug
Medicine is clashing with the Social Darwinism of the economist's "creative destruction" based on the "survival of the fittest". Competition is good for it lets the strong survive and the weak perish. To intervene against this is a crime against nature
Underlying this is the dogma that the "invisible hand" of the natural processes of the market drive it towards "self-regulating equilibrium" created by Darwinian forces of market competition. Quote from Prof Nouriel Roubini: Crisis Economics ISBN: 9780241956922 ImageImage
Market intervention is thus an unnatural perversion that undermines the invisible hand of the processes driving the market towards self-regulating equilibrium. It undermines the survival of the fittest to destroy the "wealth of nations"
Read 20 tweets
1 Apr 20
"Cytokine Storm". The idiot's buzzword of the week. It makes you sound smarter if you say it often enough. When I first heard of it in 1994 it sounded AMAZING! Then this RCT came out showing it increased mortality. Ouch nejm.org/doi/full/10.10…
Next came rhAPC (drotrecogin). Don't knock out the immune system: we need it to survive. APC has signalling properties to modulate inflammation. NEJM PROWESS was touted a success! nejm.org/doi/full/10.10…
Just as we were celebrating and retrospective analyses showed efficacy correlated with drotrecogin reducing Il-6 levels, bad news came in and the dream turned sour nejm.org/doi/full/10.10…
Read 33 tweets

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