New COVID variant detected in South Africa and 7 other countries - Europe incl -most mutated variant so far
Is it worse?
The paper: The continuous evolution of SARS-CoV-2 in South Africa: a new lineage with rapid accumulation of mutations of concern and global detection
Is it worse?
The paper: The continuous evolution of SARS-CoV-2 in South Africa: a new lineage with rapid accumulation of mutations of concern and global detection
From discussion: Many of the shared mutations have been associated with improved ACE2 binding (N501Y)25–29 or furin cleavage (H655Y and P681H/R)30–32, and reduced neutralization activity (particularly Y144del, 242-244del, and E484K)17,33–39, providing sufficient cause for concern
of continued transmission of this variant. Future work aims to determine the functional impact of these mutations, which likely include neutralizing antibody escape, and to investigate whether their combination confers a replicative fitness advantage over the Delta variant.
The pre-print medrxiv.org/content/10.110… and updated: medrxiv.org/content/10.110…
South Africa has been doing amazing stuff. We have good ice cream though!
JPost article: m.jpost.com/health-science…
South Africa has been doing amazing stuff. We have good ice cream though!
JPost article: m.jpost.com/health-science…
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