I have a new @medRxivpreprint that should be of interest to the #longevity community. We show how to predict risk for cardiovascular disease & all-cause mortality from a routine abdominal CT using deep learning. Accuracy on par with CAC score. Thread cont..medrxiv.org/content/10.110…
In this case the scans were taken for CT colonoscopy. The accuracy of the risk prediction is on par with that obtained from a CAC score Cardiac CT scan, but without the additional cost & radiation dose. CT scans contain a wealth of health data which is currently mostly utilized.
Biomarkers that can be extracted from CT scans include visceral/subcutaneous fat ratio, plaque burden, vascular inflammation level, muscle bulk and density, bone mineral density, liver volume and fat fraction, pancreas volume and fat fraction... [ see moreisdifferent.com/assets/literat… ]
In the future, I hope people will be able to download their scans from their healthcare provider at home and run a bunch of AI tools to learn more about their bodies and what preventative measures they specifically might benefit from. #DecentralizedRadiology
Alternatively, the AI tools may be run in the clinic, although that requires FDA approval, a financial incentive to purchase and maintain the necessary software & hardware, and a doctor willing to provide the info to the patient.

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More from @moreisdifferent

4 Sep
I'm calling on @Twitter to streamline threading & introduce an AI-powered autothread feature, so people can migrate their long-form commenting from Facebook to Twitter. The idea is to use AI to automatically chunk text into ~280 characters, & an option to display it seamlessly...
I find Facebook almost impossible to use.. to the extent that I sometimes wonder if I'm going crazy. Yesterday I tried to post something three times - once on my desktop and twice on my phone. I ended up posting the same thing twice yesterday. I like pages to load fast, too...
Autothreading solves an obvious problem - it's a pain to make threads. Yes it forces you to be more concise, which is good, especially for people who aren't great writers, but I feel many thoughts don't get written b/c of the added time & energy involved.
Read 5 tweets
2 Sep
Any #LongCOVID study without a control group is trash. (I've seen several)

Many of the top long COVID symptoms are very common.. [fatigue, anxiety, feeling worried/sad (40% of adolescents), headache, dizziness, shortness of breath]

many symptoms can be psychosomatic, also
.@FT headline is completely misleading... I looked at the paper (preprint) (researchsquare.com/article/rs-798…) and I can't find anywhere that "1 in 7 have Long COVID" (~14.5%) is the conclusion Image
None of this is to suggest that Long COVID isn't real, I definitely think it is, I'm just calling out the sloppy scholarship / reporting.
Read 4 tweets
31 Jul 20
Some failure modes for #GPT3. It seems GPT3 lacks common sense explanatory theories and therefore can’t extrapolate to new situations. Ie it lacks “good explanations” in the sense of @DavidDeutschOxf, which he defines (a bit vaguely) as “hard-to-vary”. 1/n
rationalconspiracy.com/2020/07/31/fun…
Explanatory theories don’t have to be as all-encompassing and as difficult to apply as the law of physics. Rather, they can be “common sense understandings” ("background knowledge") which is generalizable. Some examples would be that that liquids cause things to be wet.. 2/n
& that some objects are flammable, which means they can catch fire, but not if they are wet. As generalizable rules tied into other generalizable rules, we are reluctant to vary them. So for instance (taking an example by Deutsch), if we see a magician cut a person in half.. 3/n
Read 6 tweets

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