💡BREAKING—CDC study confirms the NIH-Moderna #COVID19 vaccine is more effective against #DeltaVariant hospitalizations than Pfizer-BioNTech or Johnson & Johnson. Vaccine efficacy for Delta🏥—Moderna 95%, Pfizer 80%, J&J 60%. VE also higher in age <74!🧵 cdc.gov/mmwr/volumes/7…
2) “Overall, VE against COVID-19 hospital- ization was 86%. VE was significantly lower among adults aged ≥75 years (76%) than among those aged 18–74 years (89%) (Table). The difference in VE point estimates between age groups was similar for Pfizer-BioNTech and Moderna vaccines”
3) “Across all ages, VE was significantly higher among Moderna vaccine recipients (95%) than among Pfizer-BioNTech (80%) or Janssen (60%) vaccine recipients.”
4) Is this difference also true for ER visits too? Yes. For ER—“VE was highest among Moderna vaccine recipients (92%), followed by Pfizer-BioNTech vaccine recipients (77%), and was lowest (65%) for Janssen vaccine recipients (Table).”
5) What about all breakthrough infections? Well, CDC itself doesn’t track all cases nationwide. But luckily, Oklahoma tracks breakthroughs by vaccine type - and in this other report, Moderna also had the lowest vaccine breakthrough rates for total infections!
6) Show more proof? Moderna also produced 2.6x more antibodies against the #SARSCoV2 virus than Pfizer in another Belgian study! We think this is because Moderna’s standard dose is 100 microgram while Pfizer’s is 30 mcg. Many scientists acknowledge this + Moderna longer time gap.
7) Another study from Minnesota found an even bigger difference between Moderna and Pfizer… for breakthroughs, ➡️ Moderna had HALF as many breakthrough infections as Pfizer! Look at the graph!
8) Let’s still remember unvaccinated are still 11x more likely to die of #COVID19. Thus, any vaccine is still leaps and bounds better than no vaccine. washingtonpost.com/health/2021/09…
9) Moderna is also developing 4 variant adapted variant-specific spike vaccines! One for #DeltaVariant, one for #BetaVariant, one for Beta+Delta, and one for Beta+original!
10) Where else have we seen fewer breakthroughs with Moderna? DC health department also noticed it a month ago… much much lower than J&J, and somewhat lower than Pfizer.
It’s been an active debate for a while—but the clue were all there for us epidemiologists watching closely.
11) Moderna 3rd shot booster’s EUA is obviously coming soon. But there is a bug debate whether to EUA authorize it as a full standard 100 mcg dose or to cut it to 50 mcg dose for the booster. I hope 100 mcg! google.com/amp/s/www.wsj.…
12) excited for the new booster data from Israel. See thread 🧵 below 👇
⚠️NO RARE BEEF!—@USDA suddenly admits (after Q&A pestering) that 120F cooked beef🥩patties experimentally inoculated with H5N1 virus still had surviving virus.
➡️“Cooking to… 120° F did show that there was virus still in the cooked hamburger patty, although at reduced levels."
2) Initially the @USDA only stated that no virus survived cooking to 160 F and 145 F. But they didn’t volunteer the 120 F rare cooking temperature results! Only after more questioning did they reveal 120 F virus survival. But so many folks eat rare meat! 🥩 DISCLOSURE CRITICAL!
UPDATE—Solar Storm hits the highest level of G5, the first in over 2 decade, which could knock out power to grids and disrupt GPS. A coronal mass ejection of G5 was also what the infamous “Carrington Event” was in 1859. But it depends on magnetic 🧲 polarity of each CME wave. NOAA warned earlier today that CME storms tend to be even stronger on the latter half of a storm wave. Let’s hope the next two days won’t be as extreme as the Carrington Event. #solarstorm
3) We are potentially in for a wild weekend. We haven’t been hit with this many CMEs in a long ass time. Nor has NOAA alerted with a GEOMAGNETIC STORM WATCH in over 20 years.
⚡️INBOUND SOLAR STORMS—5x mega coronal mass ejections - CMEs - that can knock out power are going to be slamming at Earth 🌍 between Friday and Sunday this weekend. Earth has only been hit with 3 previous severe CMEs in last 4 years. But we are gonna get 5x G4 CMEs in 3 days!😳
2) Let this sink — this is the first GEOMAGNETIC STORM WATCH since 2005!
Folks - this is serious - it can knock out not only electricity but it can theoretically knock out airplanes ✈️ too!
3) Folks- it’s possible. Not only can it cause higher radiation and knock out communications, but a strong CME can knock out airliner avionics. “according to reports by aviation regulators, the issue is not whether it will happen, but when” 😳 thedailybeast.com/how-a-solar-st…
Things are not going well with whooping cough (pertussis). Childhood vaccinations plummeting in the UK 🇬🇧, and kids also have weakened immune systems post-COVID. And it’s not even autumn 🍂.
HT @1goodtern
2) Also… let’s not forget the “m” word. Because masks do work if society takes it seriously.
3) unless we systematically solve the. chronic lack of public health infrastructure, new outbreaks will continue. We shouldn’t just learn to live with it.
⚠️New sudden outbreak of MERS coronavirus with HUMAN TO HUMAN transmission—WHO has put out an outbreak bulletin regarding 3 cases in Saudi Arabia 🇸🇦 who contracted MERS (with zero contact with camels). All 3 were hospitalized and intubated. Index case has died in just 11 days from the onset of cough and a runny nose. ➡️Here where it gets interesting—the other 2 cases, found via vigorous contact tracing—both likely contracted it from the index case in the hospital—one shared a hospital room with the index case, while the other merely visited the same hospital’s ER—but he was NOT in the same hospital ward as the index case! Given second case was in a completely separate ward of the hospital, it makes me think it was likely #airborne transmission.
Shouldn’t we all masking in hospitals? @CDCgov’s idiotic HICPAC committee that sets hospital safety standards meantime wants to water them down. Someone should share this with the HICPAC folks, thanks. And demand @CDCDirector to get serious about public health again.
2) previously, WHO’s Feb bulletin of Aug 2023-Feb 2024 only reported 4 cases, 2 had camel🐪 contact. None of the previous 4 had any linkages (ie no human to human transmission evidence). Thus, this new hospital-derived outbreak is concerning. who.int/emergencies/di…
3) it seems the Index case’s only overlap with Case #3 was on April 4th— the day they both went to the same hospital’s ER. But otherwise they were in different wards. And by the time the 3rd case went to the ICU on April 15th, the index case was already dead (died on April 11th). So it wasn’t ICU exposure. It was the ER—➡️why which why EVERYONE NEEDS TO WEAR MASKS IN THE ER DAMNIT! 🔥