With school vaccination becoming mandatory for 15 and above in Sind, there are pervasive vaccine myths galore. 𧡠google.com/amp/s/www.geo.β¦
First that children donβt need vaccine. On average 1/5 infected are children, & 1/3 of those are asymptomatic & potential spreaders. So even if children are less likely to be sick, many will indirectly benefit from their vaccination such as younger kids, immunodeficiency etc.
Of course there are direct benefits to children as well, as vaccine will reduce the chance an individual child gets Covid-19, decreasing disruption caused by school closures.
Also, not all children are immune to the virus. In high mortality countries like Pakistan, every child death counts. In Pakistan with poor registration, we think the numbers are grossly underreported. google.com/amp/s/www.thenβ¦
For example, in a sentinel surveillance of childrenβs hospitals and wards conducted by @Qalb2Abbas and colleagues, the death rates are high. This data is predelta, but delta has been bad elsewhere for children google.com.pk/amp/s/www.aljaβ¦
Another myth is regarding the vaccines not being safe and causing harm. Common side effects such as pain at injection site, tiredness, headache, muscle or joint pain, and fever and chills are also are usually transient (<48 hours)
Of the millions of doses of #COVID-19 vaccine given, a few hundred cases of myocarsitis and pericardium have been reported, so are rare. Almost all are mild and resolve quickly. In contrast, MISC caused post-Covid in adolescents is much more severe cdc.gov/mis/index.html
Some parents are worried about long-term side effects. I see unrelated pics of thalidomide toxicity on SM wrongly attributed to vaccination.Truth is vaccines are awesome for kids, decreasing death & disability from measles, polio, smallpox etc. Why would Covid19π be different?
Another myth is that the vaccines have been rolled out without adequate research. However upto 6 months of safety data has been presented to EUA agencies and several trials are on way to publication. nejm.org/doi/full/10.10β¦
Finally, issue of parental right 2 refuse vaccine. One can weigh presumed individual benefit of not vaccinating with the risks of lockdowns, filled up hospitals & drained resources, death & emergence of variants & see that refusing π is a 0 sum game. 𧡠end.
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Itβs back to school (hybrid with 50% attendance for my kids) from Monday in Sind. I see so much anxiety, especially among parents of young children, considering that children are not vaccinated and most adults arenβt either. Hereβs what we can do 1/n
Check with your school principal and class teacher to ensure every adult- yes every adult, be it a teacher, guard, helper or cleaner, is vaccinated. 2/n
Demand for physical distancing in your childβs classroom. This is only possible with smaller class sizes. Demand for smaller classes from your childβs school administration. 3/n
@AmbroggioPhD Agreed. Not a diagnostics expert but I know the following 1) This discussion is not new and has been ongoing among diagnostics folks, now coming to public view. 2) CT values can matter but converting it to a viral load equivalent is an oversimplification 1/n
@AmbroggioPhD 3) Each machine behaves differently and therefore the amplification being talked about is also going to vary. We are not aware of any standard curve quantifying viral load against CT values 2/n
@AmbroggioPhD 4) Generally speaking, lower CT means more virus but higher CT isnβt necessarily the opposite- it can have different connotations depending on whether itβs an initial test, or a repeat after 7 days, importantly days this symptom onset. 3/n
3 trials conducted in Africa demonstrated effectiveness of MDA-AZT for reduction of child mortality rates. Results were compelling enough for @WHO to review the evidence. AZT may impact mortality in countries with β¬οΈU5MR by reducing diarrhoea, pneumonia and malaria 3/n
2/ Pakistan- fifth most populous country in the world, first among LMICs to see the pandemic in late February 2020 . Now >269000 confirmed cases with over 5500 deaths, the largest number seen in Karachi, its largest city. Here is what Karachi is like in relation to Pakistan
3/ Testing rates have been low in some areas and under reporting of cases due to fear and stigma of the disease and omission of mild symptomatic and asymptomatic cases. telegraph.co.uk/global-health/β¦
1-So as most of you know, we published in @NEJM this week. This was so important for us for many reasons but fist a recap/summary of the paper.nejm.org/doi/full/10.10β¦
2/In low resource settings, WHO recommends standard of care for management of common illnesses in non-school going children. These illnesses include diarrhoea, pneumonia, malnutrition ; among others.
3/ Pneumonia is commonly called ARI ( acute respiratory illness) and classified into no, mild or severe pneumonia. For our study we decided to study mild pneumonia.